HitPredict

Interactor 1: MMP3 (P08254)
Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1)
Gene: MMP3

Interactor 2: TIMP3 (P35625)
Metalloproteinase inhibitor 3 (Protein MIG-5) (Tissue inhibitor of metalloproteinases 3) (TIMP-3)
Gene: TIMP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 26186194, 28514442
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hemopexin~TIMP, Peptidase_M10~TIMP
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0031012 - extracellular matrix
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 477
Hs

1 211
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024