HitPredict

Interactor 1: EF1A (P02994)
Elongation factor 1-alpha (EF-1-alpha) (Eukaryotic elongation factor 1A) (eEF1A) (Translation elongation factor 1A)
Gene: TEF1

Interactor 2: GCN1 (P33892)
eIF-2-alpha kinase activator GCN1 (General control non-derepressible protein 1) (Translational activator GCN1)
Gene: GCN1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	16429126, 22404850
Identification Methods	tandem affinity purification, cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0034198 - cellular response to amino acid starvation GO:0043022 - ribosome binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 458 Sc			1 2672
+	Sc
		367696 EF1A_YEAST (1-443): 0: 538: 100.00		EF3A_YEAST (1321-1710): 6.99e-83: 299: 22.87
+	Hs
		672081 EF1A1_HUMAN (1-457): 0: 548: 80.44		2AAA_HUMAN (1315-1936): 3.9e-70: 250: 14.42
+	Sc
		368480 EF1A_YEAST (1-443): 0: 538: 100.00		NEW1_YEAST (1361-1636): 7.06e-35: 149: 18.95
+	Sc
		367933 EF1A_YEAST (1-443): 0: 538: 100.00		UTP20_YEAST (1367-2411): 3.05e-15: 85.2: 11.49
+	Hs
		932767 EF1A1_HUMAN (1-457): 0: 548: 80.44		CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54
+	Hs
		984383 EF1A2_HUMAN (1-457): 0: 545: 79.35		CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54
+	Zm
		35290 B6UHJ4_MAIZE (1-446): 6.39e-177: 504: 73.66		A0A1D6LKF6_MAIZE (2204-2604): 1.01e-14: 82.1: 9.81