Interactor 1: SYA (P00957)
Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Protein lactyltransferase) (EC 6.-.-.-)
Gene: alaS
Interactor 2: TOP1 (P06612)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Swivelase) (Untwisting enzyme)
Gene: topA
Species: Escherichia coli K-12
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.60 | 0.536 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15690043 |
| Identification Methods | tandem affinity purification, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0008270 - zinc ion binding |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
