HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 499
+	Hs
		372534 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ERF3B_HUMAN (1-499): 0: 558: 93.79
+	Hs
		371721 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		EF1A1_HUMAN (70-498): 2.73e-175: 502: 38.29
+	Hs
		371835 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		EF1A2_HUMAN (70-498): 1.28e-173: 498: 37.16
+	Mm
		373663 MYC_MOUSE (1-454): 1.16e-117: 353: 89.01		EF1A1_MOUSE (70-498): 2.82e-175: 502: 38.29
+	Hs
		373590 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		HBS1L_HUMAN (3-496): 2.58e-164: 482: 38.11
+	Hs
		405755 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		ERF3A_HUMAN (1-499): 0: 566: 100.00
+	Hs
		406375 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		ERF3B_HUMAN (1-499): 0: 558: 93.79
+	Hs
		406035 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		EF1A1_HUMAN (70-498): 2.73e-175: 502: 38.29
+	Hs
		406092 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		EF1A2_HUMAN (70-498): 1.28e-173: 498: 37.16