HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: SERPH (P19324)
Serpin H1 (47 kDa heat shock protein) (Collagen-binding protein) (Colligin) (Serine protease inhibitor J6)
Gene: Serpinh1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Serpin~Trypsin
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Mm			1 417
+	Hs
		428671 TRY1_HUMAN (1-257): 2.47e-109: 317: 31.92		SPB8_HUMAN (42-408): 2.89e-149: 429: 30.67
+	Hs
		177775 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		A1AT_HUMAN (4-409): 6.51e-157: 450: 27.07
+	Mm
		430527 Q9Z1R9_MOUSE (7-256): 2.63e-109: 317: 33.47		A1AT1_MOUSE (28-409): 5.24e-147: 425: 24.55
+	Hs
		344148 KLK1_HUMAN (5-257): 1.35e-96: 285: 33.21		A1AT_HUMAN (4-409): 6.51e-157: 450: 27.07
+	Hs
		344349 KLK13_HUMAN (28-255): 9.6e-98: 288: 34.47		AACT_HUMAN (9-409): 3.67e-155: 446: 24.15
+	Hs
		344274 KLK2_HUMAN (1-256): 3.23e-97: 287: 32.59		AACT_HUMAN (9-409): 3.67e-155: 446: 24.15
+	Hs
		371463 KLKB1_HUMAN (3-256): 5.99e-100: 306: 30.30		IPSP_HUMAN (17-408): 7.61e-147: 425: 27.14
+	Hs
		177841 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		SERPH_HUMAN (34-417): 6.65e-148: 428: 96.35
+	Hs
		225959 KLK8_HUMAN (7-255): 2.15e-98: 289: 35.55		SERPH_HUMAN (34-417): 6.65e-148: 428: 96.35
+	Hs
		344097 KLK1_HUMAN (5-257): 1.35e-96: 285: 33.21		ANT3_HUMAN (23-408): 3.24e-148: 430: 22.31
+	Hs
		719387 KLK13_HUMAN (28-255): 9.6e-98: 288: 34.47		SPB6_HUMAN (42-408): 1.81e-148: 427: 29.52
+	Hs
		589593 KLK2_HUMAN (1-256): 3.23e-97: 287: 32.59		SPB6_HUMAN (42-408): 1.81e-148: 427: 29.52
+	Hs
		397636 KLK2_HUMAN (1-256): 3.23e-97: 287: 32.59		IPSP_HUMAN (17-408): 7.61e-147: 425: 27.14
+	Hs
		714770 TRY3_HUMAN (9-257): 4.36e-104: 305: 32.14		SPB12_HUMAN (41-408): 1.02e-138: 404: 27.48
+	Mm
		1141519 KLK8_MOUSE (6-255): 1.29e-96: 285: 32.42		SPB6_MOUSE (42-408): 1.23e-146: 423: 28.31
+	Mm
		936828 TM11E_MOUSE (25-253): 5.55e-98: 294: 32.20		IPSP_MOUSE (44-408): 7.14e-140: 406: 26.95
+	Hs
		1218311 TM11E_HUMAN (25-253): 1.73e-96: 290: 32.20		SPA12_HUMAN (6-411): 1.18e-139: 406: 24.76
+	Hs
		344100 GRAA_HUMAN (25-249): 7.27e-51: 168: 38.53		ANT3_HUMAN (23-408): 3.24e-148: 430: 22.31
+	Hs
		421277 KLK13_HUMAN (28-255): 9.6e-98: 288: 34.47		GDN_HUMAN (41-408): 2.78e-33: 130: 24.41
+	Hs
		421257 KLK2_HUMAN (1-256): 3.23e-97: 287: 32.59		GDN_HUMAN (41-408): 2.78e-33: 130: 24.41