Protein: AP1M1
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)

Gene: AP1M1
Organism: Homo sapiens
Interactions: 204
UniProt ID: Q9BXS5

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

940571

AP1S2
AP-1 complex subunit sigma-2

4

20

High-throughput

0.903

High

989100

AP2B1
AP-2 complex subunit beta

4

20

Small-scale

0.896

High

1083305

AP1B1
AP-1 complex subunit beta-1

3

20

Small-scale

0.849

High

1417339

AP1M2
AP-1 complex subunit mu-2

3

11

High-throughput

0.847

High

225852

AP1G1
AP-1 complex subunit gamma-1

3

20

Small-scale

0.827

High

218726

TGON2
Trans-Golgi network integral membrane protein 2

6

7

Small-scale

0.731

High

1202496

RUN3A
RUN domain-containing protein 3A

5

5

High-throughput

0.723

High

900490

FXR2
RNA-binding protein FXR2

4

6

High-throughput

0.705

High

1388851

HOOK2
Protein Hook homolog 2

4

8

Small-scale

0.700

High

1252079

RN19B
E3 ubiquitin-protein ligase RNF19B

4

7

High-throughput

0.698

High

159832

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

5

High-throughput

0.698

High

1335271

NECP1
Adaptin ear-binding coat-associated protein 1

1

4

High-throughput

0.691

High

1399536

AP1S3
AP-1 complex subunit sigma-3

1

20

High-throughput

0.691

High

1417338

SAR1B
Small COPII coat GTPase SAR1B

1

3

High-throughput

0.691

High

1276298

ATG9A
Autophagy-related protein 9A

4

6

Small-scale

0.676

High

1385949

TIFA
TRAF-interacting protein with FHA domain-containing protein A

4

0

High-throughput

0.675

High

229366

ZBT14
Zinc finger and BTB domain-containing protein 14

3

1

High-throughput

0.675

High

950387

KR107
Keratin-associated protein 10-7

3

3

High-throughput

0.675

High

1104665

IKZF1
DNA-binding protein Ikaros

3

1

High-throughput

0.675

High

1230239

K1C40
Keratin, type I cytoskeletal 40

3

8

High-throughput

0.675

High

1417322

ZRAN1
Ubiquitin thioesterase ZRANB1

3

2

High-throughput

0.653

High

1117333

ARFRP
ADP-ribosylation factor-related protein 1

1

3

Small-scale

0.647

High

1385037

ZBT8A
Zinc finger and BTB domain-containing protein 8A

4

7

High-throughput

0.644

High

965423

AP1S1
AP-1 complex subunit sigma-1A

1

19

High-throughput

0.618

High

1417315

NECP2
Adaptin ear-binding coat-associated protein 2

1

4

High-throughput

0.618

High

212859

ZBT43
Zinc finger and BTB domain-containing protein 43

3

7

High-throughput

0.616

High

1385690

ENTR1
Endosome-associated-trafficking regulator 1

2

0

High-throughput

0.613

High

1159941

MEA1
Male-enhanced antigen 1

3

2

High-throughput

0.607

High

294888

BCAR3
Breast cancer anti-estrogen resistance protein 3

2

5

High-throughput

0.606

High

572186

TRI27
Zinc finger protein RFP

2

1

High-throughput

0.606

High

900137

FXR1
RNA-binding protein FXR1

2

6

High-throughput

0.606

High

950654

KR108
Keratin-associated protein 10-8

2

2

High-throughput

0.606

High

1214081

KIF24
Kinesin-like protein KIF24

2

5

High-throughput

0.606

High

1327653

NKAP
NF-kappa-B-activating protein

2

1

High-throughput

0.606

High

1357742

TRI41
E3 ubiquitin-protein ligase TRIM41

2

1

High-throughput

0.606

High

1398704

AP4AT
AP-4 complex accessory subunit Tepsin

2

2

High-throughput

0.606

High

1417300

BACH2
Transcription regulator protein BACH2

2

4

High-throughput

0.606

High

1417301

SDCB2
Syntenin-2

2

3

High-throughput

0.606

High

1417314

DISC1
Disrupted in schizophrenia 1 protein

2

1

High-throughput

0.606

High

1417325

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

8

High-throughput

0.606

High

1417329

LZTS1
Leucine zipper putative tumor suppressor 1

2

7

High-throughput

0.606

High

300035

CBPD
Carboxypeptidase D

2

0

High-throughput

0.602

High

1417326

FBX4
F-box only protein 4

2

0

High-throughput

0.602

High

335739

RPGF3
Rap guanine nucleotide exchange factor 3

1

0

High-throughput

0.589

High

242806

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.584

High

363815

EGFR
Epidermal growth factor receptor

2

11

High-throughput

0.584

High

351597

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

0

High-throughput

0.580

High

617245

ATF4
Cyclic AMP-dependent transcription factor ATF-4

2

0

High-throughput

0.580

High

685336

PAX6
Paired box protein Pax-6

2

0

High-throughput

0.580

High

1036862

SP4
Transcription factor Sp4

2

0

High-throughput

0.580

High

1329261

GCSAM
Germinal center-associated signaling and motility protein

2

0

High-throughput

0.580

High

1331724

NECA1
N-terminal EF-hand calcium-binding protein 1

2

0

High-throughput

0.580

High

1396160

LRAT2
Protein LRATD2

2

0

High-throughput

0.580

High

1417313

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1417320

ZN219
Zinc finger protein 219

2

0

High-throughput

0.580

High

1417332

AXIN2
Axin-2

2

0

High-throughput

0.580

High

278553

VAMP4
Vesicle-associated membrane protein 4

1

3

Small-scale

0.573

High

1138013

TNIP1
TNFAIP3-interacting protein 1

1

6

High-throughput

0.573

High

1411276

LZTS2
Leucine zipper putative tumor suppressor 2

1

10

High-throughput

0.573

High

581726

MYOD1
Myoblast determination protein 1

2

1

High-throughput

0.553

High

601980

ZNF8
Zinc finger protein 8

2

1

High-throughput

0.553

High

1256731

NKAP1
Uncharacterized protein NKAPD1

2

1

High-throughput

0.553

High

1274003

OLIG3
Oligodendrocyte transcription factor 3

2

2

High-throughput

0.553

High

1348478

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.553

High

1417304

ZSC16
Zinc finger and SCAN domain-containing protein 16

2

2

High-throughput

0.553

High

1417305

ZBTB3
Zinc finger and BTB domain-containing protein 3

2

8

High-throughput

0.553

High

1417310

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

2

1

High-throughput

0.553

High

1417323

RSP14
Radial spoke head 14 homolog

2

3

High-throughput

0.553

High

833021

ETV6
Transcription factor ETV6

1

0

High-throughput

0.549

High

462612

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.541

High

483201

CLCA
Clathrin light chain A

1

5

High-throughput

0.536

High

483387

CLCB
Clathrin light chain B

1

5

High-throughput

0.536

High

556320

CADH1
Cadherin-1

1

4

High-throughput

0.536

High

650938

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

1

High-throughput

0.536

High

1177246

MICA
MHC class I polypeptide-related sequence A

1

2

High-throughput

0.536

High

1324858

LRC25
Leucine-rich repeat-containing protein 25

1

2

High-throughput

0.536

High

1417317

GTSE1
G2 and S phase-expressed protein 1

1

2

High-throughput

0.536

High

1417334

PCDB7
Protocadherin beta-7

1

3

High-throughput

0.536

High

1417335

PCDB3
Protocadherin beta-3

1

3

High-throughput

0.536

High

1294563

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

3

High-throughput

0.523

High

1312494

PHC2
Polyhomeotic-like protein 2

1

1

High-throughput

0.523

High

1316980

FAM9B
Protein FAM9B

1

1

High-throughput

0.523

High

1335952

ZBT44
Zinc finger and BTB domain-containing protein 44

1

2

High-throughput

0.523

High

252373

TLR2
Toll-like receptor 2

1

0

High-throughput

0.513

High

390159

ALBU
Albumin

1

0

High-throughput

0.513

High

625598

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

642283

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.513

High

867392

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

966831

1433G
14-3-3 protein gamma

1

0

High-throughput

0.513

High

1148934

SC23A
Protein transport protein Sec23A

1

0

High-throughput

0.513

High

1398668

SPT33
Spermatogenesis-associated protein 33

1

0

High-throughput

0.513

High

1417327

VANG2
Vang-like protein 2

1

0

Small-scale

0.504

High

508558

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.501

High

574116

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

1

Small-scale

0.501

High

1006677

SRPK2
SRSF protein kinase 2

1

8

High-throughput

0.501

High

1417302

KI13A
Kinesin-like protein KIF13A

1

4

Small-scale

0.501

High

593485

PGFRA
Platelet-derived growth factor receptor alpha

1

6

High-throughput

0.500

High

302944

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

2

High-throughput

0.489

High

799455

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.481

High

949987

KR103
Keratin-associated protein 10-3

1

2

High-throughput

0.481

High

1088790

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

7

Small-scale

0.481

High

1098535

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

7

Small-scale

0.481

High

1132426

CASP8
Caspase-8

1

2

High-throughput

0.481

High

1197075

AMOT
Angiomotin

1

5

High-throughput

0.481

High

173312

XPO1
Exportin-1

1

13

High-throughput

0.479

High

178385

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

190166

TNC18
Trinucleotide repeat-containing gene 18 protein

1

1

High-throughput

0.479

High

249383

MPZL2
Myelin protein zero-like protein 2

1

1

High-throughput

0.479

High

325092

HEXI1
Protein HEXIM1

1

3

High-throughput

0.479

High

412560

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.479

High

488855

FURIN
Furin

1

1

High-throughput

0.479

High

537839

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.479

High

541670

FGFR1
Fibroblast growth factor receptor 1

1

7

High-throughput

0.479

High

562374

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

1040914

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

High-throughput

0.479

High

1066768

NCBP1
Nuclear cap-binding protein subunit 1

1

1

High-throughput

0.479

High

1067683

EP300
Histone acetyltransferase p300

1

4

High-throughput

0.479

High

1107170

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1114198

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1132948

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

4

High-throughput

0.479

High

1138596

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1324916

RHG18
Rho GTPase-activating protein 18

1

2

High-throughput

0.479

High

1367185

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

1397398

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

1403335

RUFY1
RUN and FYVE domain-containing protein 1

1

8

High-throughput

0.479

High

1411696

RIOK1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

1417243

TMM59
Transmembrane protein 59

1

1

Small-scale

0.479

High

1417299

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1417308

PRD16
Histone-lysine N-methyltransferase PRDM16

1

3

High-throughput

0.479

High

1417312

ANLN
Anillin

1

2

High-throughput

0.479

High

1417318

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1417333

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

2

Small-scale

0.479

High

716

A0A087WWI0
Leucine-rich melanocyte differentiation-associated protein

1

1

High-throughput

0.470

High

2870

A0A0C4DG62
ADP-ribosylation factor-like protein 6-interacting protein 4

1

1

High-throughput

0.470

High

59932

A2BDD9
AMOT protein

1

5

High-throughput

0.470

High

1238959

Q6NVI2
CASP8 protein

1

1

High-throughput

0.470

High

300073

OR2B3
Putative olfactory receptor 2B3

1

0

High-throughput

0.458

High

731587

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

884394

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

1137259

CND1
Condensin complex subunit 1

1

0

High-throughput

0.458

High

1306916

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.458

High

1380138

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1386950

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

High-throughput

0.458

High

1417328

CAH14
Carbonic anhydrase 14

1

0

High-throughput

0.458

High

1417319

PAK5
Serine/threonine-protein kinase PAK 5

1

6

High-throughput

0.457

High

262297

SCN2B
Sodium channel regulatory subunit beta-2

1

1

High-throughput

0.445

High

484218

PGFRB
Platelet-derived growth factor receptor beta

1

6

High-throughput

0.445

High

530328

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

935090

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.445

High

1048387

ACVR1
Activin receptor type-1

1

1

High-throughput

0.445

High

1180958

HFE
Hereditary hemochromatosis protein

1

2

High-throughput

0.445

High

1234937

PKHA7
Pleckstrin homology domain-containing family A member 7

1

4

High-throughput

0.445

High

1239044

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.445

High

1417331

SL9A8
Sodium/hydrogen exchanger 8

1

1

High-throughput

0.445

High

1417336

PCDG5
Protocadherin gamma-A5

1

3

High-throughput

0.445

High

1226800

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

1

1

High-throughput

0.439

High

1417303

LRMDA
Leucine-rich melanocyte differentiation-associated protein

1

1

High-throughput

0.439

High

1417324

HOOK1
Protein Hook homolog 1

1

8

Small-scale

0.439

High

106593

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

373055

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.437

High

589601

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

607072

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.437

High

696414

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

769083

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

879433

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.437

High

1100334

TIF1B
Transcription intermediary factor 1-beta

1

4

High-throughput

0.437

High

1255383

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1314396

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.437

High

1417309

SACA1
Sperm acrosome membrane-associated protein 1

1

1

High-throughput

0.437

High

591915

LYAM3
P-selectin

1

0

Small-scale

0.426

High

844863

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.426

High

1309980

MFS6L
Major facilitator superfamily domain-containing protein 6-like

1

0

High-throughput

0.426

High

1313825

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.426

High

1346776

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.426

High

945162

CORO7
Coronin-7

1

2

Small-scale

0.408

High

343802

LDOC1
Protein LDOC1

4

0

High-throughput

0.367

High

1133299

MTF1
Metal regulatory transcription factor 1

2

0

High-throughput

0.334

High

600070

ZNF19
Zinc finger protein 19

2

0

High-throughput

0.316

High

640617

MK
Midkine

2

0

High-throughput

0.316

High

1220490

F219B
Protein FAM219B

2

0

High-throughput

0.316

High

1327329

ZN276
Zinc finger protein 276

2

0

High-throughput

0.316

High

1330222

ZN655
Zinc finger protein 655

2

0

High-throughput

0.316

High

1346563

RP9
Retinitis pigmentosa 9 protein

2

0

High-throughput

0.316

High

1348375

THAP6
THAP domain-containing protein 6

2

0

High-throughput

0.316

High

1386102

EVI5L
EVI5-like protein

2

0

High-throughput

0.316

High

1400965

PURB
Transcriptional regulator protein Pur-beta

2

0

High-throughput

0.316

High

1417306

ZN552
Zinc finger protein 552

2

0

High-throughput

0.316

High

1417307

ROP1A
Ropporin-1A

2

0

High-throughput

0.316

High

1417311

ZCC17
Zinc finger CCHC domain-containing protein 17

2

0

High-throughput

0.316

High

1417316

SPAT6
Spermatogenesis-associated protein 6

2

0

High-throughput

0.316

High

1417321

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.316

High

1417337

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

0

High-throughput

0.316

High

1315780

CE57L
Centrosomal protein CEP57L1

1

0

High-throughput

0.299

High

1400220

PNMA5
Paraneoplastic antigen-like protein 5

1

0

High-throughput

0.299

High

1417330

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.299

High

484635

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1328400

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

1337449

CG057
Uncharacterized protein C7orf57

1

0

High-throughput

0.251

Low

251290

TDRD6
Tudor domain-containing protein 6

1

0

High-throughput

0.249

Low

869226

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.249

Low

1405230

MTEF1
Transcription termination factor 1, mitochondrial

1

0

High-throughput

0.249

Low

63775

KRBA1
Protein KRBA1

1

0

High-throughput

0.232

Low

1145672

RCN1
Reticulocalbin-1

1

0

High-throughput

0.232

Low

1238063

S18B1
MFS-type transporter SLC18B1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025