HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29467282, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 2725
+	Hs
		371153 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		FLNA_HUMAN (147-2725): 0: 1228: 35.27
+	Hs
		372273 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		Q60FE5_HUMAN (147-2725): 0: 1228: 35.27
+	Hs
		277984 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		FLNB_HUMAN (146-2725): 0: 1196: 35.23
+	Hs
		405785 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		FLNA_HUMAN (147-2725): 0: 1228: 35.27
+	Hs
		371041 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ACTN1_HUMAN (13-382): 4.65e-121: 409: 26.04
+	Hs
		224574 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ACTN4_HUMAN (16-387): 1.42e-119: 405: 26.68
+	Hs
		371784 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		372621 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SYNE1_HUMAN (33-344): 6.38e-100: 364: 28.65
+	Hs
		370875 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		FINC_HUMAN (1545-2724): 4.55e-64: 246: 13.76
+	Hs
		405738 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		ACTN1_HUMAN (13-382): 4.65e-121: 409: 26.04
+	Hs
		406408 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		SYNE1_HUMAN (33-344): 6.38e-100: 364: 28.65
+	Hs
		1028744 SRBP2_HUMAN (124-446): 2.15e-34: 138: 12.54		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		372705 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		TITIN_HUMAN (1661-2636): 1.15e-09: 66.7: 10.95
+	Hs
		406440 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		TITIN_HUMAN (1661-2636): 1.15e-09: 66.7: 10.95