HitPredict

Interactor 1: GFAP (P03995)
Glial fibrillary acidic protein (GFAP)
Gene: GFAP

Interactor 2: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	16443603, 30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0031175 - neuron projection development GO:0044297 - cell body GO:0097386 - glial cell projection
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 430 Mm			1 733
+	Rn
		581945 GFAP_RAT (1-429): 9.89e-145: 420: 96.28		TAU_RAT (1-733): 1.67e-78: 268: 88.46
+	Rn
		94169 GFAP_RAT (1-429): 9.89e-145: 420: 96.28		F1LST4_RAT (1-732): 4.29e-78: 268: 88.58
+	Hs
		496206 GFAP_HUMAN (1-429): 3.01e-144: 419: 90.97		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		443287 VIME_HUMAN (4-428): 4.42e-141: 413: 56.54		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		496488 PERI_HUMAN (46-426): 1.2e-106: 325: 56.14		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		443464 VIME_HUMAN (4-428): 4.42e-141: 413: 56.54		ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10
+	Rn
		581925 AINX_RAT (42-384): 1.22e-78: 253: 50.29		TAU_RAT (1-733): 1.67e-78: 268: 88.46
+	Rn
		94148 AINX_RAT (42-384): 1.22e-78: 253: 50.29		F1LST4_RAT (1-732): 4.29e-78: 268: 88.58
+	Hs
		497096 AINX_HUMAN (34-384): 2.02e-82: 263: 49.16		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		203200 VIME_HUMAN (4-428): 4.42e-141: 413: 56.54		SYNJ1_HUMAN (336-712): 5.99e-10: 65: 13.02
+	Hs
		496199 K2C5_HUMAN (33-377): 9.85e-77: 251: 32.86		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		443800 VIME_HUMAN (4-428): 4.42e-141: 413: 56.54		TARA_HUMAN (7-691): 9.27e-09: 61.2: 9.57
+	Hs
		422332 NFM_HUMAN (59-375): 1.63e-72: 246: 47.50		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		359457 K2C6A_HUMAN (33-393): 7.54e-75: 245: 31.15		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		422133 NFL_HUMAN (42-375): 3.85e-74: 243: 47.32		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		203197 K2C8_HUMAN (39-422): 1.86e-133: 394: 32.53		SYNJ1_HUMAN (336-712): 5.99e-10: 65: 13.02
+	Hs
		781878 PERI_HUMAN (46-426): 1.2e-106: 325: 56.14		ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10
+	Hs
		203211 PERI_HUMAN (46-426): 1.2e-106: 325: 56.14		SYNJ1_HUMAN (336-712): 5.99e-10: 65: 13.02
+	Hs
		965108 AINX_HUMAN (34-384): 2.02e-82: 263: 49.16		ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10
+	Hs
		422380 NFM_HUMAN (59-375): 1.63e-72: 246: 47.50		ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10