HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019899 - enzyme binding GO:0031333 - negative regulation of protein-containing complex assembly
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 410
+	Hs
		373599 RAF1_HUMAN (1-648): 0: 652: 100.00		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		522736 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		433233 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		411972 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		506858 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		433228 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		523214 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		433509 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95