HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: ERCC3 (P19447)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB (TFIIH subunit XPB) (EC 5.6.2.4) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA 3'-5' helicase/translocase XPB) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)
Gene: ERCC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006915 - apoptotic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 782
+	Hs
		181676 RAF1_HUMAN (1-648): 0: 652: 100.00		DDX3Y_HUMAN (201-677): 7.95e-102: 329: 10.85
+	Hs
		374851 RAF1_HUMAN (1-648): 0: 652: 100.00		DDX47_HUMAN (273-769): 5.98e-101: 321: 13.19
+	Hs
		374887 RAF1_HUMAN (1-648): 0: 652: 100.00		DDX31_HUMAN (204-653): 9.57e-87: 294: 13.92
+	Hs
		374963 RAF1_HUMAN (1-648): 0: 652: 100.00		DDX18_HUMAN (189-720): 1.43e-85: 287: 14.88
+	Hs
		488767 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		DDX17_HUMAN (225-769): 2.71e-110: 354: 12.85
+	Hs
		488565 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		DDX5_HUMAN (198-775): 3.03e-108: 345: 12.56