HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30442766, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0044877 - protein-containing complex binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 760
+	Hs
		375068 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		390515 RAB8A_HUMAN (4-185): 1.75e-84: 249: 36.02		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		390585 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		374326 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		390525 RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		390516 RAB2A_HUMAN (4-185): 5.47e-74: 223: 31.52		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		390517 RAB14_HUMAN (4-185): 1.88e-73: 222: 29.35		TFR1_HUMAN (1-760): 0: 971: 100.00