HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: RBM34 (P42696)
RNA-binding protein 34 (RNA-binding motif protein 34)
Gene: RBM34

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.659

Property	Details
Experiments	36244648, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 430
+	Hs
		374066 RAF1_HUMAN (1-648): 0: 652: 100.00		TIAR_HUMAN (173-404): 3.64e-40: 149: 15.44
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (19-287): 2.32e-22: 101: 13.01
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (277-372): 1.58e-18: 90: 25.77
+	Hs
		374671 RAF1_HUMAN (1-648): 0: 652: 100.00		MSI2H_HUMAN (106-303): 1.67e-16: 81.8: 10.45
+	Hs
		201649 RAF1_HUMAN (1-648): 0: 652: 100.00		MSI1H_HUMAN (79-287): 1.31e-15: 79.6: 8.02
+	Hs
		374678 RAF1_HUMAN (1-648): 0: 652: 100.00		DAZP1_HUMAN (164-286): 2.14e-15: 79.5: 15.45
+	Hs
		374467 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP2_HUMAN (280-360): 2.36e-10: 63.2: 39.51
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (19-287): 2.32e-22: 101: 13.01
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (277-372): 1.58e-18: 90: 25.77
+	Hs
		412206 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		SF3B4_HUMAN (179-374): 6.16e-55: 189: 22.00
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (19-287): 2.32e-22: 101: 13.01
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (277-372): 1.58e-18: 90: 25.77
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (277-372): 2.42e-16: 83: 27.84
+	Hs
		523106 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MSI2H_HUMAN (106-303): 1.67e-16: 81.8: 10.45
+	Hs
		433441 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		MSI2H_HUMAN (106-303): 1.67e-16: 81.8: 10.45