HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: LUM (P51884)
Lumican (Keratan sulfate proteoglycan lumican) (KSPG lumican)
Gene: LUM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38496616
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_6~Pkinase
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 648 Hs			1 338
+	Hs
		374998 RAF1_HUMAN (1-648): 0: 652: 100.00		FLRT3_HUMAN (162-338): 2.13e-18: 87.9: 24.16
+	At
		95369 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		BAME1_ARATH (2-280): 3.48e-33: 131: 17.69
+	At
		83707 Y5182_ARATH (2-643): 1.52e-168: 506: 16.09		BAME1_ARATH (2-280): 3.48e-33: 131: 17.69
+	At
		221787 Y5181_ARATH (10-622): 5.26e-163: 491: 16.03		BAME1_ARATH (2-280): 3.48e-33: 131: 17.69
+	At
		84374 MEE39_ARATH (1-647): 2.66e-161: 487: 16.36		BAME1_ARATH (2-280): 3.48e-33: 131: 17.69
+	At
		84517 Y4245_ARATH (3-643): 3.48e-161: 487: 15.77		BAME1_ARATH (2-280): 3.48e-33: 131: 17.69
+	At
		83480 Y1756_ARATH (2-631): 5.57e-161: 486: 15.78		BAME1_ARATH (2-280): 3.48e-33: 131: 17.69
+	At
		95392 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		BAME2_ARATH (101-337): 9.17e-22: 98.4: 17.43
+	At
		221812 SERK2_ARATH (77-644): 3.51e-157: 468: 17.99		BAME1_ARATH (2-280): 3.48e-33: 131: 17.69
+	At
		84531 Y4245_ARATH (3-643): 3.48e-161: 487: 15.77		IRK_ARATH (2-252): 3.74e-24: 105: 18.71
+	At
		1325563 Y5181_ARATH (10-622): 5.26e-163: 491: 16.03		BAME2_ARATH (101-337): 9.17e-22: 98.4: 17.43
+	At
		1278223 BAK1_ARATH (77-647): 6.91e-163: 482: 17.30		IRK_ARATH (2-252): 3.74e-24: 105: 18.71
+	At
		84185 Y2289_ARATH (12-644): 3.44e-159: 481: 16.54		IRK_ARATH (2-252): 3.74e-24: 105: 18.71
+	At
		84533 Y4245_ARATH (3-643): 3.48e-161: 487: 15.77		BAME2_ARATH (101-337): 9.17e-22: 98.4: 17.43
+	At
		84525 Y4245_ARATH (3-643): 3.48e-161: 487: 15.77		RGI1_ARATH (136-337): 2.4e-20: 94.1: 20.38
+	At
		85102 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		RGI2_ARATH (3-158): 8.99e-11: 65.3: 15.66
+	At
		95366 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		RGI4_ARATH (2-154): 7.22e-09: 59.1: 17.18
+	At
		99036 Y2451_ARATH (1-644): 5.92e-162: 488: 16.04		RGI4_ARATH (2-154): 7.22e-09: 59.1: 17.18
+	At
		84208 Y2289_ARATH (12-644): 3.44e-159: 481: 16.54		BRL2_ARATH (68-206): 1.64e-09: 61.4: 20.71
+	At
		99017 BAK1_ARATH (77-647): 6.91e-163: 482: 17.30		RGI4_ARATH (2-154): 7.22e-09: 59.1: 17.18