HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: M2OM (Q02978)
Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11)
Gene: SLC25A11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31980649, 36244648, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 314
+	Hs
		373923 RAF1_HUMAN (1-648): 0: 652: 100.00		TXTP_HUMAN (13-310): 1.49e-88: 269: 21.67
+	Hs
		542866 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		M2OM_HUMAN (1-314): 1.66e-99: 297: 100.00
+	Hs
		375037 RAF1_HUMAN (1-648): 0: 652: 100.00		DIC_HUMAN (14-207): 1.66e-30: 118: 20.92
+	Hs
		488629 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TXTP_HUMAN (13-310): 1.49e-88: 269: 21.67
+	Dm
		507716 KRAF1_DROME (45-647): 6.35e-165: 491: 44.98		ADT_DROME (3-307): 1.21e-90: 274: 18.53
+	Hs
		375063 RAF1_HUMAN (1-648): 0: 652: 100.00		S2513_HUMAN (3-122): 5.08e-23: 101: 20.83
+	Hs
		373508 RAF1_HUMAN (1-648): 0: 652: 100.00		ADT2_HUMAN (7-108): 1.65e-10: 62.9: 18.45
+	Hs
		433326 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		M2OM_HUMAN (1-314): 1.66e-99: 297: 100.00
+	Hs
		412140 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		M2OM_HUMAN (1-314): 1.66e-99: 297: 100.00
+	Hs
		488825 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		S2513_HUMAN (3-122): 5.08e-23: 101: 20.83
+	Hs
		488549 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		ADT3_HUMAN (7-109): 3.4e-11: 64.8: 21.15
+	Hs
		397239 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		ADT2_HUMAN (7-108): 1.65e-10: 62.9: 18.45
+	Hs
		518227 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		ADT3_HUMAN (7-109): 3.4e-11: 64.8: 21.15