HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: BORG4 (Q9H3Q1)
Cdc42 effector protein 4 (Binder of Rho GTPases 4)
Gene: CDC42EP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 356
+	Hs
		375948 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1145108 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		374926 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		375415 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		1025809 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		373884 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		374529 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		956255 RAB2A_HUMAN (4-185): 5.47e-74: 223: 31.52		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		158718 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86