HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34017080, 36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 471
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		374607 RAF1_HUMAN (1-648): 0: 652: 100.00		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		374285 RAF1_HUMAN (1-648): 0: 652: 100.00		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		488722 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		374768 RAF1_HUMAN (1-648): 0: 652: 100.00		RBM4B_HUMAN (75-182): 7.1e-09: 59.3: 35.71
+	Hs
		488730 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (66-459): 5.94e-61: 211: 13.88
+	Hs
		433366 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Mm
		763405 FYN_MOUSE (342-607): 7.04e-40: 155: 35.29		RAVR1_MOUSE (76-226): 7e-12: 69.8: 25.75