HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: BAG1 (Q99933)
BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)
Gene: BAG1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	8692945, 11231577
Identification Methods	pull down, two hybrid, affinity chromatography technology, coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0043066 - negative regulation of apoptotic process
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 345
+	Rn
		69523 RAF1_RAT (1-648): 0: 648: 98.30		BAG1_RAT (1-345): 0: 518: 69.83