HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: DRG1 (Q9Y295)
Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-)
Gene: DRG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36244648, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 367
+	Hs
		373939 RAF1_HUMAN (1-648): 0: 652: 100.00		DRG2_HUMAN (3-367): 2.86e-134: 389: 57.26
+	Hs
		374950 RAF1_HUMAN (1-648): 0: 652: 100.00		OLA1_HUMAN (44-364): 1.3e-81: 256: 16.92
+	Hs
		374832 RAF1_HUMAN (1-648): 0: 652: 100.00		GTPB4_HUMAN (1-311): 1.51e-64: 218: 17.38
+	Hs
		59553 RAF1_HUMAN (1-648): 0: 652: 100.00		GTPBA_HUMAN (29-202): 4.08e-46: 163: 28.57
+	Zm
		28105 A0A1D6JP61_MAIZE (273-627): 7.9e-105: 342: 29.14		A0A1D6PLR6_MAIZE (3-367): 1.93e-130: 380: 56.45