Protein: ARX1
Probable metalloprotease ARX1 (EC 3.-.-.-) (Associated with ribosomal export complex protein 1)

Gene: ARX1
Organism: Saccharomyces cerevisiae S288C
Interactions: 207
UniProt ID: Q03862

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748898

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

22

1

Small-scale

0.765

High

973447

NOG1
Nucleolar GTP-binding protein 1

20

2

Small-scale

0.763

High

864675

NOG2
Nucleolar GTP-binding protein 2

18

5

Small-scale

0.762

High

977788

IF6
Eukaryotic translation initiation factor 6

15

1

Small-scale

0.760

High

535104

RL3
Large ribosomal subunit protein uL3

14

1

Small-scale

0.759

High

766691

NUG1
Nuclear GTP-binding protein NUG1

13

5

Small-scale

0.756

High

630887

NLE1
Ribosome assembly protein 4

12

2

Small-scale

0.755

High

977773

RLP24
Ribosome biogenesis protein RLP24

12

3

Small-scale

0.753

High

859627

LSG1
Large subunit GTPase 1

9

5

Small-scale

0.752

High

703108

MRT4
Ribosome assembly factor MRT4

10

3

Small-scale

0.750

High

641051

RL5
Large ribosomal subunit protein uL18

9

3

Small-scale

0.748

High

776501

RLP7
Ribosome biogenesis protein RLP7

9

3

Small-scale

0.748

High

399619

RLA0
Large ribosomal subunit protein uL10

8

3

Small-scale

0.747

High

756384

NMD3
60S ribosomal export protein NMD3

29

0

Small-scale

0.735

High

977792

MEX67
mRNA export factor MEX67

16

0

Small-scale

0.729

High

860872

PESC
Pescadillo homolog

15

0

Small-scale

0.727

High

768042

NSA2
Ribosome biogenesis protein NSA2

12

0

Small-scale

0.725

High

810590

ALB1
Ribosome biogenesis protein ALB1

11

0

Small-scale

0.725

High

861403

SDA1
Protein SDA1

11

0

Small-scale

0.724

High

756862

RIX1
Pre-rRNA-processing protein RIX1

11

0

Small-scale

0.723

High

977774

BUD20
Bud site selection protein 20

10

0

Small-scale

0.723

High

977784

NOP53
Ribosome biogenesis protein NOP53

12

0

Small-scale

0.722

High

482930

RL35A
Large ribosomal subunit protein uL29A

6

2

Small-scale

0.719

High

733921

RPF2
Ribosome biogenesis protein RPF2

10

0

Small-scale

0.719

High

698184

AFG2
ATPase family gene 2 protein

8

0

Small-scale

0.717

High

970192

PVH1
Tyrosine-protein phosphatase YVH1

10

0

Small-scale

0.717

High

383332

RL25
Large ribosomal subunit protein uL23

6

1

Small-scale

0.717

High

754181

CIC1
Proteasome-interacting protein CIC1

9

0

Small-scale

0.716

High

710721

MTR2
mRNA transport regulator MTR2

8

0

Small-scale

0.709

High

687995

IMB3
Importin subunit beta-3

5

1

Small-scale

0.706

High

499062

RL4A
Large ribosomal subunit protein uL4A

5

3

Small-scale

0.702

High

977783

MDN1
Midasin

6

0

Small-scale

0.695

High

865672

IPI3
Pre-rRNA-processing protein IPI3

4

2

Small-scale

0.686

High

866256

NOP15
Ribosome biogenesis protein 15

3

3

High-throughput

0.662

High

564364

RL8A
Large ribosomal subunit protein eL8A

6

2

Small-scale

0.658

High

971897

NU116
Nucleoporin NUP116/NSP116

3

6

Small-scale

0.658

High

829686

RL4B
Large ribosomal subunit protein uL4B

3

3

Small-scale

0.656

High

971873

NU100
Nucleoporin NUP100/NSP100

5

6

Small-scale

0.648

High

769355

SSB2
Ribosome-associated molecular chaperone SSB2

3

5

High-throughput

0.643

High

479170

RL43B
Large ribosomal subunit protein eL43B

3

1

Small-scale

0.640

High

481065

RL23B
Large ribosomal subunit protein uL14B

3

1

Small-scale

0.640

High

715623

SQT1
Ribosome assembly protein SQT1

3

3

Small-scale

0.640

High

742976

GBLP
Small ribosomal subunit protein RACK1

3

6

High-throughput

0.640

High

784216

RL10
Large ribosomal subunit protein uL16

3

2

Small-scale

0.640

High

492304

HSP71
Heat shock protein SSA1

3

4

High-throughput

0.633

High

865490

JJJ1
J protein JJJ1

3

1

Small-scale

0.633

High

755253

IPI1
Pre-rRNA-processing protein IPI1

3

0

Small-scale

0.628

High

645122

RL16A
Large ribosomal subunit protein uL13A

4

3

Small-scale

0.617

High

767081

ARB1
ABC transporter ATP-binding protein ARB1

3

0

Small-scale

0.616

High

405814

RL26A
Large ribosomal subunit protein uL24A

4

3

Small-scale

0.613

High

404691

RL7A
Large ribosomal subunit protein uL30A

2

3

High-throughput

0.611

High

865749

NOP13
Nucleolar protein 13

2

3

High-throughput

0.611

High

977759

ARX1
Probable metalloprotease ARX1

3

0

Small-scale

0.609

High

859982

CGR1
rRNA-processing protein CGR1

3

0

Small-scale

0.606

High

595066

NUP1
Nucleoporin NUP1

2

3

Small-scale

0.602

High

965481

NOP3
Serine/arginine

2

3

Small-scale

0.601

High

667270

RL8B
Large ribosomal subunit protein eL8B

3

2

High-throughput

0.599

High

478975

RL20B
Large ribosomal subunit protein eL20B

3

1

High-throughput

0.585

High

481414

RL2A
Large ribosomal subunit protein uL2A

3

2

High-throughput

0.585

High

645271

RL16B
Large ribosomal subunit protein uL13B

3

3

Small-scale

0.585

High

481221

RL1A
Large ribosomal subunit protein uL1A

2

2

Small-scale

0.584

High

634442

SPB1
27S pre-rRNA

2

2

High-throughput

0.584

High

977791

RL11B
Large ribosomal subunit protein uL5B

2

3

Small-scale

0.584

High

408103

RS13
Small ribosomal subunit protein uS15

2

1

High-throughput

0.571

High

691279

MYO4
Myosin-4

2

0

High-throughput

0.563

High

763586

ECM1
Shuttling pre-60S factor ECM1

2

0

Small-scale

0.559

High

792562

UTP10
U3 small nucleolar RNA-associated protein 10

2

0

High-throughput

0.559

High

145783

RL36B
Large ribosomal subunit protein eL36B

2

1

High-throughput

0.558

High

972286

RL21A
Large ribosomal subunit protein eL21A

2

3

Small-scale

0.558

High

977777

TMA16
Translation machinery-associated protein 16

2

0

High-throughput

0.547

High

977779

RRS1
Regulator of ribosome biosynthesis

2

0

High-throughput

0.547

High

830652

NUP42
Nucleoporin NUP42

2

4

Small-scale

0.543

High

743661

HMT1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.541

High

763481

ERP2
Protein ERP2

2

3

High-throughput

0.537

High

376918

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

4

Small-scale

0.536

High

534835

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.536

High

676341

XPO1
Exportin-1

1

3

High-throughput

0.536

High

472376

RL31A
Large ribosomal subunit protein eL31A

2

1

High-throughput

0.533

High

481697

RL18B
Large ribosomal subunit protein eL18B

2

2

High-throughput

0.533

High

977778

RS10A
Small ribosomal subunit protein eS10A

2

2

High-throughput

0.533

High

482782

RL19B
Large ribosomal subunit protein eL19

2

3

Small-scale

0.521

High

860253

RL26B
Large ribosomal subunit protein uL24B

2

3

Small-scale

0.521

High

859422

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.513

High

977767

FKBP4
FK506-binding protein 4

1

0

High-throughput

0.513

High

977782

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.513

High

866139

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.504

High

541921

NSP1
Nucleoporin NSP1

1

5

Small-scale

0.501

High

691663

NUP2
Nucleoporin NUP2

1

2

Small-scale

0.501

High

774372

NU159
Nucleoporin NUP159

1

4

Small-scale

0.501

High

969358

NUP49
Nucleoporin NUP49/NSP49

1

4

Small-scale

0.501

High

409919

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.493

High

763525

NUP60
Nucleoporin NUP60

1

0

Small-scale

0.480

High

141507

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

387933

RL39
Large ribosomal subunit protein eL39

1

2

High-throughput

0.479

High

405267

RL17A
Large ribosomal subunit protein uL22A

1

2

High-throughput

0.479

High

407294

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

408452

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.479

High

413692

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

471932

RL27B
Large ribosomal subunit protein eL27B

1

3

High-throughput

0.479

High

477648

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

1

High-throughput

0.479

High

480292

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

482443

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

597892

PWP1
Periodic tryptophan protein 1

1

3

Small-scale

0.479

High

605140

XRN1
5'-3' exoribonuclease 1

1

1

Small-scale

0.479

High

632071

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

645631

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

663200

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

688812

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.479

High

730100

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

743309

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.479

High

752652

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

767632

GLE2
mRNA export factor GLE2

1

2

Small-scale

0.479

High

767721

IMB4
Importin subunit beta-4

1

1

High-throughput

0.479

High

797564

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

810286

RL17B
Large ribosomal subunit protein uL22B

1

2

High-throughput

0.479

High

810908

MTR4
ATP-dependent RNA helicase DOB1

1

3

Small-scale

0.479

High

819877

TRF5
Poly(A) RNA polymerase protein 1

1

1

Small-scale

0.479

High

820153

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

824757

RL37A
Large ribosomal subunit protein eL37A

1

1

High-throughput

0.479

High

846332

RL37B
Large ribosomal subunit protein eL37B

1

1

High-throughput

0.479

High

863695

PAP2
Poly(A) RNA polymerase protein 2

1

1

Small-scale

0.479

High

953515

RL34A
Large ribosomal subunit protein eL34A

1

2

High-throughput

0.479

High

967736

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

975813

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

976845

HAS1
ATP-dependent RNA helicase HAS1

1

1

High-throughput

0.479

High

977761

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

977763

DHR1
Probable ATP-dependent RNA helicase DHR1

1

4

High-throughput

0.479

High

977766

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

977769

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.479

High

977770

REH1
Cytoplasmic 60S subunit biogenesis factor REH1

1

1

High-throughput

0.479

High

977771

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

977772

NOC3
Nucleolar complex-associated protein 3

1

1

High-throughput

0.479

High

977775

NOP12
Nucleolar protein 12

1

4

High-throughput

0.479

High

977785

YRA1
RNA annealing protein YRA1

1

4

High-throughput

0.479

High

977786

RL7B
Large ribosomal subunit protein uL30B

1

3

High-throughput

0.479

High

977787

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.479

High

524436

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

558236

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

606739

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

624169

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

628421

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

634749

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

688404

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

733675

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

746263

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

753939

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

754900

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.458

High

757021

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

759439

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

774585

BMT5
25S rRNA

1

0

High-throughput

0.458

High

774818

AIR1
Protein AIR1

1

0

Small-scale

0.458

High

778847

NOP2
25S rRNA

1

0

High-throughput

0.458

High

797388

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

Small-scale

0.458

High

811344

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

859499

NSA1
Ribosome biogenesis protein NSA1

1

0

Small-scale

0.458

High

974311

ESP1
Separin

1

0

High-throughput

0.458

High

977760

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

977762

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.458

High

977764

PUF6
Pumilio homology domain family member 6

1

0

Small-scale

0.458

High

977765

RQC1
Ribosome quality control complex subunit 1

1

0

High-throughput

0.458

High

977768

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

977776

SGO1
Shugoshin

1

0

High-throughput

0.458

High

977780

RSA1
Ribosome assembly 1 protein

1

0

Small-scale

0.458

High

471440

RL11A
Large ribosomal subunit protein uL5A

1

3

Small-scale

0.445

High

494854

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

512570

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

544346

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

705602

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

754674

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.445

High

766185

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.445

High

822998

NUP57
Nucleoporin NUP57

1

4

Small-scale

0.439

High

358243

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

382796

RL24A
Large ribosomal subunit protein eL24A

1

3

Small-scale

0.437

High

404906

RL9A
Large ribosomal subunit protein uL6A

1

3

High-throughput

0.437

High

405060

RL6B
Large ribosomal subunit protein eL6B

1

3

High-throughput

0.437

High

406058

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.437

High

406400

RL15A
Large ribosomal subunit protein eL15A

1

2

High-throughput

0.437

High

406606

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.437

High

426132

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

471233

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

471826

RL27A
Large ribosomal subunit protein eL27A

1

3

High-throughput

0.437

High

480863

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

481985

RL12B
Large ribosomal subunit protein uL11B

1

2

High-throughput

0.437

High

700605

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

706468

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

732784

RL14A
Large ribosomal subunit protein eL14A

1

2

High-throughput

0.437

High

753703

RL14B
Large ribosomal subunit protein eL14B

1

2

High-throughput

0.437

High

762522

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

770450

RL13B
Large ribosomal subunit protein eL13B

1

2

High-throughput

0.437

High

775087

RL34B
Large ribosomal subunit protein eL34B

1

2

High-throughput

0.437

High

846306

RL9B
Large ribosomal subunit protein uL6B

1

3

High-throughput

0.437

High

959857

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

970348

RL6A
Large ribosomal subunit protein eL6A

1

3

High-throughput

0.437

High

977781

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

977789

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.437

High

977790

RL13A
Large ribosomal subunit protein eL13A

1

2

High-throughput

0.437

High

424691

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

556274

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

703730

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.426

High

977162

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.426

High

696554

DSS4
Protein DSS4

1

0

High-throughput

0.279

Low

479278

RL44B
Large ribosomal subunit protein eL42B

1

0

High-throughput

0.249

Low

482994

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.249

Low

691848

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.249

Low

540152

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

707921

GCN1
eIF-2-alpha kinase activator GCN1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024