HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0010628 - positive regulation of gene expression GO:0030857 - negative regulation of epithelial cell differentiation
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 504
+	Hs
		374137 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47
+	Hs
		374915 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		WWP1_HUMAN (4-504): 4.94e-105: 336: 14.63
+	Hs
		375841 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47
+	Hs
		374457 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		NEDD4_HUMAN (40-504): 3.86e-95: 315: 19.26
+	Hs
		373827 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		NEDD4_HUMAN (40-504): 3.86e-95: 315: 19.26
+	Hs
		861997 RAB1A_HUMAN (4-187): 3.14e-74: 223: 34.36		YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00
+	Hs
		861991 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00
+	Hs
		958021 RAB14_HUMAN (4-184): 2.96e-72: 219: 29.51		WWP1_HUMAN (4-504): 4.94e-105: 336: 14.63
+	Hs
		375277 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		NEDD4_HUMAN (40-504): 3.86e-95: 315: 19.26
+	Hs
		375700 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		RHG12_HUMAN (14-441): 7.79e-69: 238: 13.76
+	Hs
		374148 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		MAGI1_HUMAN (69-305): 3.34e-38: 151: 18.32
+	Ce
		654000 LET60_CAEEL (1-189): 1.64e-85: 251: 74.60		Q8MXF0_CAEEL (93-422): 1.58e-36: 146: 15.06
+	Hs
		375854 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		MAGI1_HUMAN (69-305): 3.34e-38: 151: 18.32
+	Dm
		874122 RALA_DROME (4-182): 3.41e-60: 187: 52.22		Q9W2L2_DROME (1-267): 3.64e-40: 157: 21.01
+	Hs
		902229 RAB13_HUMAN (4-186): 4.35e-72: 218: 36.76		WWOX_HUMAN (166-263): 7.43e-29: 120: 30.61