Interactor 1: PROC (P04070)
Vitamin K-dependent protein C (EC 3.4.21.69) (Anticoagulant protein C) (Autoprothrombin IIA) (Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide]
Gene: PROC

Interactor 2: PROS (P07225)
Vitamin K-dependent protein S
Gene: PROS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 28514442
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_CA~FXa_inhibition, FXa_inhibition~FXa_inhibition, FXa_inhibition~Trypsin
Common GO terms GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005796 - Golgi lumen
GO:0007596 - blood coagulation
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 461
Hs

1 676
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Last updated: 15 Jul 2024