Interactor 1: CSF2 (P04141)
Granulocyte-macrophage colony-stimulating factor (GM-CSF) (Colony-stimulating factor) (CSF) (Molgramostin) (Sargramostim)
Gene: CSF2

Interactor 2: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 8934574, 9190901
Identification Methods electrophoretic mobility supershift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0010744 - positive regulation of macrophage derived foam cell differentiation
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 144
Hs

1 968
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024