Interactor 1: SOMA (P01241)
Somatotropin (Growth hormone) (GH) (GH-N) (Growth hormone 1) (Pituitary growth hormone)
Gene: GH1
Interactor 2: PRLR (P16471)
Prolactin receptor (PRL-R)
Gene: PRLR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 7984244 |
| Identification Methods | x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EpoR_lig-bind~Hormone_1 |
| Common GO terms | GO:0005576 - extracellular region GO:0007259 - cell surface receptor signaling pathway via JAK-STAT GO:0019221 - cytokine-mediated signaling pathway GO:0031904 - endosome lumen GO:0046872 - metal ion binding |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
