Protein: SOMA
Somatotropin (Growth hormone) (GH) (GH-N) (Growth hormone 1) (Pituitary growth hormone)

Gene: SOMA, GH1
Organism: Homo sapiens
Interactions: 93
UniProt ID: P01241

Gene Ontology (top 5):
GO:0005125 - cytokine activity
GO:0005131 - growth hormone receptor binding
GO:0005148 - prolactin receptor binding
GO:0005179 - hormone activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

377164

GHR
Growth hormone receptor

7

2

Small-scale

0.961

High

377163

CSH2
Chorionic somatomammotropin hormone 2

2

9

High-throughput

0.789

High

377162

CSH1
Chorionic somatomammotropin hormone 1

2

9

High-throughput

0.712

High

377170

PRLR
Prolactin receptor

1

2

Small-scale

0.647

High

377154

SOMA
Somatotropin

1

9

High-throughput

0.618

High

377161

LKHA4
Leukotriene A-4 hydrolase

1

1

High-throughput

0.515

High

377155

S10A6
Protein S100-A6

1

5

Small-scale

0.501

High

377176

S100P
Protein S100-P

1

5

Small-scale

0.501

High

377179

LYOX
Protein-lysine 6-oxidase

1

5

Small-scale

0.501

High

377231

TREM2
Triggering receptor expressed on myeloid cells 2

1

0

Small-scale

0.480

High

377165

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.479

High

377167

BMP1
Bone morphogenetic protein 1

1

1

Small-scale

0.479

High

377171

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

377234

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

1

High-throughput

0.479

High

377237

STRAP
Serine-threonine kinase receptor-associated protein

1

1

High-throughput

0.470

High

128122

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

High-throughput

0.458

High

210829

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.458

High

377157

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

377158

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.458

High

377159

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.458

High

377168

PLAK
Junction plakoglobin

1

0

High-throughput

0.458

High

377185

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.458

High

377192

GDIB
Rab GDP dissociation inhibitor beta

1

0

High-throughput

0.458

High

377194

PSA
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.458

High

377202

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

0

High-throughput

0.458

High

377203

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

377204

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

377205

CYC
Cytochrome c

1

0

High-throughput

0.458

High

377206

DHSO
Sorbitol dehydrogenase

1

0

High-throughput

0.458

High

377208

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

377222

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.458

High

298280

DNJC8
DnaJ homolog subfamily C member 8

1

1

High-throughput

0.437

High

377173

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.437

High

377181

TKT
Transketolase

1

1

High-throughput

0.437

High

377182

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.437

High

377210

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

1

High-throughput

0.437

High

377221

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

1

High-throughput

0.437

High

128367

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

2

Small-scale

0.373

High

377219

F161A
Protein FAM161A

1

0

High-throughput

0.279

Low

377180

SHC1
SHC-transforming protein 1

1

0

Small-scale

0.261

Low

274429

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.249

Low

286139

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.249

Low

347452

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.249

Low

361985

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.249

Low

377156

NPM
Nucleophosmin

1

0

High-throughput

0.249

Low

377160

RHOC
Rho-related GTP-binding protein RhoC

1

0

High-throughput

0.249

Low

377166

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.249

Low

377169

DESP
Desmoplakin

1

0

High-throughput

0.249

Low

377172

GSTM3
Glutathione S-transferase Mu 3

1

0

High-throughput

0.249

Low

377174

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

377175

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.249

Low

377177

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.249

Low

377178

MK03
Mitogen-activated protein kinase 3

1

0

High-throughput

0.249

Low

377183

ECHM
Enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.249

Low

377184

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

0

High-throughput

0.249

Low

377186

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.249

Low

377187

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

0

High-throughput

0.249

Low

377188

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.249

Low

377189

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.249

Low

377190

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

377191

PSB3
Proteasome subunit beta type-3

1

0

High-throughput

0.249

Low

377193

KAD2
Adenylate kinase 2, mitochondrial

1

0

High-throughput

0.249

Low

377195

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.249

Low

377196

DEST
Destrin

1

0

High-throughput

0.249

Low

377197

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

0

High-throughput

0.249

Low

377198

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.249

Low

377199

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.249

Low

377200

MGN
Protein mago nashi homolog

1

0

High-throughput

0.249

Low

377201

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.249

Low

377207

SET
Protein SET

1

0

High-throughput

0.249

Low

377209

DSG1
Desmoglein-1

1

0

High-throughput

0.249

Low

377211

CUL2
Cullin-2

1

0

High-throughput

0.249

Low

377212

SEPT2
Septin-2

1

0

High-throughput

0.249

Low

377213

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.249

Low

377214

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.249

Low

377215

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.249

Low

377216

ADRM1
Proteasomal ubiquitin receptor ADRM1

1

0

High-throughput

0.249

Low

377217

FSCN1
Fascin

1

0

High-throughput

0.249

Low

377218

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

377220

Q75MH1
40S ribosomal protein S26

1

0

High-throughput

0.249

Low

377223

TM263
Transmembrane protein 263

1

0

High-throughput

0.249

Low

377224

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

Small-scale

0.249

Low

377225

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.249

Low

377226

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.249

Low

377227

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.249

Low

377228

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.249

Low

377229

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.249

Low

377230

Q9NZ23
glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.249

Low

377232

NUDT5
ADP-sugar pyrophosphatase

1

0

High-throughput

0.249

Low

377233

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.249

Low

377235

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.249

Low

377236

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025