Protein: PRLR
Prolactin receptor (PRL-R)

Gene: PRLR
Organism: Homo sapiens
Interactions: 23
UniProt ID: P16471

Gene Ontology (top 5):
GO:0004925 - prolactin receptor activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0006694 - steroid biosynthetic process
GO:0007171 - activation of transmembrane receptor protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

596941

PRLR
Prolactin receptor

2

17

Small-scale

0.831

High

377146

PRL
Prolactin

2

2

Small-scale

0.825

High

377170

SOMA
Somatotropin

1

2

Small-scale

0.647

High

596950

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

1

High-throughput

0.606

High

584462

VAV
Proto-oncogene vav

2

20

Small-scale

0.595

High

253289

JAK2
Tyrosine-protein kinase JAK2

2

20

Small-scale

0.584

High

596942

TEC
Tyrosine-protein kinase Tec

1

20

Small-scale

0.561

High

596946

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

Small-scale

0.561

High

596952

CBP
CREB-binding protein

1

2

Small-scale

0.528

High

596954

FBW1B
F-box/WD repeat-containing protein 11

1

6

Small-scale

0.528

High

596948

H11
Histone H1.1

1

5

High-throughput

0.515

High

155073

SOCS2
Suppressor of cytokine signaling 2

1

20

Small-scale

0.479

High

155904

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.479

High

596943

STA5B
Signal transducer and activator of transcription 5B

1

20

Small-scale

0.479

High

596944

NEK3
Serine/threonine-protein kinase Nek3

1

8

Small-scale

0.479

High

596945

VAV2
Guanine nucleotide exchange factor VAV2

1

20

Small-scale

0.479

High

596947

1433Z
14-3-3 protein zeta/delta

1

7

Small-scale

0.479

High

596949

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

Small-scale

0.479

High

596953

CISH
Cytokine-inducible SH2-containing protein

1

20

Small-scale

0.479

High

596955

FBW1A
F-box/WD repeat-containing protein 1A

1

6

Small-scale

0.437

High

596956

INSI2
Insulin-induced gene 2 protein

2

0

High-throughput

0.316

High

596951

TF3A
Transcription factor IIIA

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025