HitPredict

Interactor 1: IFNG (P01579)
Interferon gamma (IFN-gamma) (Immune interferon)
Gene: IFNG

Interactor 2: STAT4 (Q14765)
Signal transducer and activator of transcription 4
Gene: STAT4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15522880, 11449378
Identification Methods	anti tag coimmunoprecipitation, electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007259 - cell surface receptor signaling pathway via JAK-STAT GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 166 Hs			1 748
+	Hs
		378419 IFNG_HUMAN (1-166): 4.27e-90: 261: 100.00		STAT1_HUMAN (1-743): 0: 931: 52.65
+	Hs
		378418 IFNG_HUMAN (1-166): 4.27e-90: 261: 100.00		STAT3_HUMAN (1-728): 0: 882: 48.24
+	Hs
		378420 IFNG_HUMAN (1-166): 4.27e-90: 261: 100.00		STAT6_HUMAN (1-747): 0: 682: 25.61