HitPredict

Interactor 1: KV3A8 (P01660)
Ig kappa chain V-III region PC 3741/TEPC 111
Gene: KV3A8

Interactor 2: GCAM (P01865)
Immunoglobulin heavy constant gamma 2A (Ig gamma-2A chain C region, membrane-bound form)
Gene: Ighg2a

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	10811933
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~V-set
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 111 Mm			1 398
+	Mm
		378764 KV2A7_MOUSE (1-111): 5.01e-47: 148: 62.50		GCAM_MOUSE (1-398): 1.8e-106: 321: 100.00
+	Mm
		378765 KV2A7_MOUSE (1-111): 5.01e-47: 148: 62.50		IGG2B_MOUSE (1-398): 1.03e-104: 316: 79.46
+	Hs
		379276 Q8N355_HUMAN (3-110): 1.73e-39: 133: 50.45		IGHG1_HUMAN (2-398): 5.85e-110: 329: 66.83
+	Hs
		378779 LV208_HUMAN (4-99): 1.69e-34: 116: 45.83		IGHG1_HUMAN (2-398): 5.85e-110: 329: 66.83
+	Mm
		378772 KV3AD_MOUSE (1-111): 1.02e-52: 162: 85.59		IGHG1_MOUSE (1-328): 2.81e-75: 238: 68.29
+	Mm
		378766 KV2A7_MOUSE (1-111): 5.01e-47: 148: 62.50		IGHG1_MOUSE (1-328): 2.81e-75: 238: 68.29
+	Mm
		378792 LV1B_MOUSE (1-110): 3.23e-40: 131: 36.36		IGHG1_MOUSE (1-328): 2.81e-75: 238: 68.29
+	Mm
		378795 LV1E_MOUSE (1-110): 3.56e-38: 126: 35.46		IGHG1_MOUSE (1-328): 2.81e-75: 238: 68.29
+	Hs
		378759 KV320_HUMAN (1-99): 3.51e-42: 136: 62.63		IGHA1_HUMAN (2-373): 3.19e-65: 214: 28.39
+	Hs
		378751 KVD40_HUMAN (1-99): 1.72e-41: 134: 58.42		IGHA1_HUMAN (2-373): 3.19e-65: 214: 28.39
+	Hs
		378750 KVD40_HUMAN (1-99): 1.72e-41: 134: 58.42		IGHM_HUMAN (3-357): 1.41e-23: 103: 19.74
+	Hs
		378780 LV208_HUMAN (4-99): 1.69e-34: 116: 45.83		IGLC1_HUMAN (5-94): 5.02e-10: 58.2: 27.66