Protein: IGHA1
Immunoglobulin heavy constant alpha 1 (Ig alpha-1 chain C region) (Ig alpha-1 chain C region BUR) (Ig alpha-1 chain C region TRO)

Gene: IGHA1
Organism: Homo sapiens
Interactions: 152
UniProt ID: P01876

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0003094 - glomerular filtration
GO:0003823 - antigen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

379615

FCAR
Immunoglobulin alpha Fc receptor

1

8

Small-scale

0.647

High

132968

MATN2
Matrilin-2

1

10

High-throughput

0.575

High

210651

KLK10
Kallikrein-10

1

8

High-throughput

0.575

High

366304

PLMN
Plasminogen

1

1

High-throughput

0.575

High

378751

KVD40
Immunoglobulin kappa variable 2D-40

1

14

High-throughput

0.575

High

378759

KV320
Immunoglobulin kappa variable 3-20

1

11

High-throughput

0.575

High

378775

LV147
Immunoglobulin lambda variable 1-47

1

17

High-throughput

0.575

High

379599

FINC
Fibronectin

1

9

High-throughput

0.575

High

379601

ALBU
Albumin

1

6

High-throughput

0.575

High

379607

HEP2
Heparin cofactor 2

1

1

High-throughput

0.575

High

379609

IGLC1
Immunoglobulin lambda constant 1

1

16

High-throughput

0.575

High

379614

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

6

High-throughput

0.575

High

379618

SC6A6
Sodium- and chloride-dependent taurine transporter

1

2

High-throughput

0.575

High

379620

TRY3
Trypsin-3

1

8

High-throughput

0.575

High

379624

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

1

4

High-throughput

0.575

High

379636

LG3BP
Galectin-3-binding protein

1

8

High-throughput

0.575

High

379655

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.575

High

379659

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

1

High-throughput

0.575

High

379678

FNDC5
Fibronectin type III domain-containing protein 5

1

5

High-throughput

0.575

High

379698

LOXL4
Lysyl oxidase homolog 4

1

3

High-throughput

0.575

High

379723

Q9UL92
Myosin-reactive immunoglobulin heavy chain variable region

1

16

High-throughput

0.575

High

379617

ITPI2
Protein ITPRID2

2

1

High-throughput

0.552

High

379702

TM237
Transmembrane protein 237

2

1

High-throughput

0.552

High

379630

GDF10
Growth/differentiation factor 10

1

0

High-throughput

0.546

High

379696

HAVR1
Hepatitis A virus cellular receptor 1

1

0

Small-scale

0.546

High

379716

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

1

0

High-throughput

0.546

High

379634

TF2B
Transcription initiation factor IIB

2

3

High-throughput

0.504

High

379647

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

2

1

High-throughput

0.504

High

379657

ICE2
Little elongation complex subunit 2

2

2

High-throughput

0.504

High

379658

HBM
Hemoglobin subunit mu

2

4

High-throughput

0.504

High

379675

FRMD1
FERM domain-containing protein 1

2

6

High-throughput

0.504

High

379676

ZN491
Zinc finger protein 491

2

1

High-throughput

0.504

High

379700

SNX27
Sorting nexin-27

2

11

High-throughput

0.504

High

379709

DDX31
ATP-dependent DNA helicase DDX31

2

8

High-throughput

0.504

High

379611

CADH1
Cadherin-1

1

3

Small-scale

0.479

High

379613

NCK1
SH2/SH3 adapter protein NCK1

1

15

Small-scale

0.479

High

379616

APC
Adenomatous polyposis coli protein

1

3

Small-scale

0.479

High

379635

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

141974

FCN1
Ficolin-1

1

5

Small-scale

0.457

High

134463

CCRL2
C-C chemokine receptor-like 2

1

12

High-throughput

0.445

High

178885

SCAM2
Secretory carrier-associated membrane protein 2

1

1

High-throughput

0.445

High

351634

SG1D1
Secretoglobin family 1D member 1

1

5

High-throughput

0.445

High

379595

K1C14
Keratin, type I cytoskeletal 14

1

11

High-throughput

0.445

High

379596

APOA1
Apolipoprotein A-I

1

3

High-throughput

0.445

High

379597

APOC1
Apolipoprotein C-I

1

2

High-throughput

0.445

High

379598

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

5

High-throughput

0.445

High

379600

TTHY
Transthyretin

1

1

High-throughput

0.445

High

379602

TRFE
Serotransferrin

1

3

High-throughput

0.445

High

379603

K2C1
Keratin, type II cytoskeletal 1

1

7

High-throughput

0.445

High

379604

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

6

High-throughput

0.445

High

379605

F13B
Coagulation factor XIII B chain

1

5

Small-scale

0.445

High

379610

CLUS
Clusterin

1

1

High-throughput

0.445

High

379612

K1C10
Keratin, type I cytoskeletal 10

1

13

High-throughput

0.445

High

379619

CCR1
C-C chemokine receptor type 1

1

12

High-throughput

0.445

High

379621

K1C9
Keratin, type I cytoskeletal 9

1

12

High-throughput

0.445

High

379623

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

4

High-throughput

0.445

High

379626

TGM4
Protein-glutamine gamma-glutamyltransferase 4

1

1

High-throughput

0.445

High

379638

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

4

High-throughput

0.445

High

379640

FADD
FAS-associated death domain protein

1

3

High-throughput

0.445

High

379644

I5P1
Inositol polyphosphate-5-phosphatase A

1

1

High-throughput

0.445

High

379646

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.445

High

379652

FBLN7
Fibulin-7

1

5

High-throughput

0.445

High

379667

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.445

High

379668

RHG12
Rho GTPase-activating protein 12

1

5

High-throughput

0.445

High

379679

AT11C
Phospholipid-transporting ATPase IG

1

2

High-throughput

0.445

High

379683

NPB
Neuropeptide B

1

2

High-throughput

0.445

High

379684

PARD3
Partitioning defective 3 homolog

1

4

High-throughput

0.445

High

379688

ITLN2
Intelectin-2

1

5

High-throughput

0.445

High

379693

PMEPA
Protein TMEPAI

1

2

High-throughput

0.445

High

379695

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.445

High

379704

EGFL8
Epidermal growth factor-like protein 8

1

13

High-throughput

0.445

High

379721

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

7

High-throughput

0.445

High

379724

HYOU1
Hypoxia up-regulated protein 1

1

4

High-throughput

0.445

High

155274

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

1

High-throughput

0.437

High

221996

NCK2
Cytoplasmic protein NCK2

1

16

Small-scale

0.437

High

277232

PITX3
Pituitary homeobox 3

1

3

Small-scale

0.437

High

379697

CK5P3
CDK5 regulatory subunit-associated protein 3

1

1

High-throughput

0.437

High

379608

CATL1
Procathepsin L

1

0

High-throughput

0.426

High

379627

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.426

High

379701

PRAP1
Proline-rich acidic protein 1

1

0

High-throughput

0.426

High

379707

SPEF2
Sperm flagellar protein 2

1

0

High-throughput

0.426

High

379714

GKN1
Gastrokine-1

1

0

High-throughput

0.426

High

379717

UNC79
Protein unc-79 homolog

1

0

High-throughput

0.426

High

67416

GOG8A
Golgin subfamily A member 8A

1

6

High-throughput

0.407

High

133836

FOXN3
Forkhead box protein N3

1

4

High-throughput

0.407

High

168950

QCR8
Cytochrome b-c1 complex subunit 8

1

1

High-throughput

0.407

High

191896

MAGB4
Melanoma-associated antigen B4

1

4

High-throughput

0.407

High

335219

CXB5
Gap junction beta-5 protein

1

7

High-throughput

0.407

High

354009

CX001
Putative transmembrane protein CXorf1

1

1

High-throughput

0.407

High

379606

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

379622

MTREX
Exosome RNA helicase MTR4

1

2

High-throughput

0.407

High

379628

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

5

High-throughput

0.407

High

379629

RCAN1
Calcipressin-1

1

1

High-throughput

0.407

High

379631

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

3

High-throughput

0.407

High

379633

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

7

High-throughput

0.407

High

379637

TWF1
Twinfilin-1

1

2

High-throughput

0.407

High

379639

STK4
Serine/threonine-protein kinase 4

1

9

High-throughput

0.407

High

379641

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.407

High

379642

RUNX2
Runt-related transcription factor 2

1

2

High-throughput

0.407

High

379643

RCAN2
Calcipressin-2

1

1

High-throughput

0.407

High

379645

COG2
Conserved oligomeric Golgi complex subunit 2

1

1

High-throughput

0.407

High

379648

CR021
UPF0711 protein C18orf21

1

6

High-throughput

0.407

High

379649

PKHG6
Pleckstrin homology domain-containing family G member 6

1

2

High-throughput

0.407

High

379650

T176B
Transmembrane protein 176B

1

2

High-throughput

0.407

High

379651

KLH22
Kelch-like protein 22

1

6

High-throughput

0.407

High

379656

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

8

High-throughput

0.407

High

379661

SFXN4
Sideroflexin-4

1

5

High-throughput

0.407

High

379663

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.407

High

379664

SPNS3
Protein spinster homolog 3

1

1

High-throughput

0.407

High

379665

CIR1
Corepressor interacting with RBPJ 1

1

6

High-throughput

0.407

High

379666

ZN695
Zinc finger protein 695

1

1

High-throughput

0.407

High

379669

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.407

High

379670

ELOA2
Elongin-A2

1

5

High-throughput

0.407

High

379671

RIBC1
RIB43A-like with coiled-coils protein 1

1

2

High-throughput

0.407

High

379673

COMD1
COMM domain-containing protein 1

1

1

High-throughput

0.407

High

379677

GDPD1
Lysophospholipase D GDPD1

1

3

High-throughput

0.407

High

379681

PNMA1
Paraneoplastic antigen Ma1

1

1

High-throughput

0.407

High

379685

CHAC2
Glutathione-specific gamma-glutamylcyclotransferase 2

1

1

High-throughput

0.407

High

379689

CRGN
Gamma-crystallin N

1

2

High-throughput

0.407

High

379690

DDX17
Probable ATP-dependent RNA helicase DDX17

1

1

High-throughput

0.407

High

379691

TANK
TRAF family member-associated NF-kappa-B activator

1

2

High-throughput

0.407

High

379692

PIGT
GPI-anchor transamidase component PIGT

1

6

High-throughput

0.407

High

379694

GTPB3
5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial

1

3

High-throughput

0.407

High

379703

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

10

High-throughput

0.407

High

379705

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.407

High

379706

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

8

High-throughput

0.407

High

379710

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

1

High-throughput

0.407

High

379712

COE2
Transcription factor COE2

1

5

High-throughput

0.407

High

379713

ZCC17
Zinc finger CCHC domain-containing protein 17

1

1

High-throughput

0.407

High

379715

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

4

High-throughput

0.407

High

379718

KLF15
Krueppel-like factor 15

1

7

High-throughput

0.407

High

379719

PHF11
PHD finger protein 11

1

10

High-throughput

0.407

High

379722

NXT1
NTF2-related export protein 1

1

1

High-throughput

0.407

High

70886

ZBBX
Zinc finger B-box domain-containing protein 1

1

0

High-throughput

0.232

Low

162075

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.232

Low

273327

NPHP4
Nephrocystin-4

1

0

High-throughput

0.232

Low

379625

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.232

Low

379632

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.232

Low

379653

EAPP
E2F-associated phosphoprotein

1

0

High-throughput

0.232

Low

379654

Q5JQP4
DNA polymerase

1

0

High-throughput

0.232

Low

379660

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.232

Low

379662

PBIR3
PABIR family member 1

1

0

High-throughput

0.232

Low

379672

TBC19
TBC1 domain family member 19

1

0

High-throughput

0.232

Low

379674

CJ053
UPF0728 protein C10orf53

1

0

High-throughput

0.232

Low

379680

TM116
Transmembrane protein 116

1

0

High-throughput

0.232

Low

379682

CC148
Coiled-coil domain-containing protein 148

1

0

High-throughput

0.232

Low

379686

RN141
RING finger protein 141

1

0

High-throughput

0.232

Low

379687

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.232

Low

379699

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

High-throughput

0.232

Low

379708

ATG5
Autophagy protein 5

1

0

High-throughput

0.232

Low

379711

KT3K
Ketosamine-3-kinase

1

0

High-throughput

0.232

Low

379720

SRTD3
SERTA domain-containing protein 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025