HitPredict

Interactor 1: S100B (P04271)
Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B)
Gene: S100B

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	12377780, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	EF-hand_1~IQ
Common GO terms	GO:0001726 - ruffle GO:0005509 - calcium ion binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0044548 - S100 protein binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 92 Hs			1 1657
+	Hs
		638938 S100P_HUMAN (1-91): 2.35e-34: 114: 50.55		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		661216 S10A2_HUMAN (2-90): 1.34e-29: 102: 44.94		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		380776 S100B_HUMAN (1-92): 9.54e-32: 107: 100.00		IQGA2_HUMAN (254-1657): 0: 1321: 54.09
+	Hs
		596359 S10A4_HUMAN (3-90): 2.3e-30: 104: 47.73		RASA1_HUMAN (459-1347): 4.15e-180: 571: 13.14
+	Hs
		685185 S10AB_HUMAN (2-91): 3e-33: 112: 35.56		SYGP1_HUMAN (635-1477): 1.49e-108: 380: 12.26