Protein: KAPR
cAMP-dependent protein kinase regulatory subunit (cAPK regulatory subunit) (Bypass of cyclase mutations protein 1) (Protein kinase A regulatory subunit) (PKA regulatory subunit)

Gene: KAPR, BCY1
Organism: Saccharomyces cerevisiae S288C
Interactions: 114
UniProt ID: P07278

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0001932 - regulation of protein phosphorylation
GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

412929

KAPB
cAMP-dependent protein kinase type 2

18

20

Small-scale

0.988

High

412617

KAPA
cAMP-dependent protein kinase type 1

19

20

Small-scale

0.987

High

409586

KAPC
cAMP-dependent protein kinase type 3

10

20

Small-scale

0.974

High

425565

KAPR
cAMP-dependent protein kinase regulatory subunit

5

18

Small-scale

0.920

High

425566

LTE1
Guanine nucleotide exchange factor LTE1

1

2

High-throughput

0.691

High

425581

CSK21
Casein kinase II subunit alpha

1

9

High-throughput

0.691

High

425596

KC11
Casein kinase I homolog 1

1

10

High-throughput

0.691

High

425567

PBS2
MAP kinase kinase PBS2

1

15

High-throughput

0.647

High

425586

PHO85
Cyclin-dependent protein kinase PHO85

1

2

High-throughput

0.647

High

425597

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

13

High-throughput

0.647

High

425610

ELM1
Serine/threonine-protein kinase ELM1

1

3

High-throughput

0.647

High

425649

VHS1
Serine/threonine-protein kinase VHS1

1

2

High-throughput

0.647

High

425658

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

7

High-throughput

0.647

High

425580

HSC82
ATP-dependent molecular chaperone HSC82

3

4

Small-scale

0.640

High

425573

HSP71
Heat shock protein SSA1

3

4

Small-scale

0.624

High

425595

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

2

1

High-throughput

0.619

High

425594

RAD53
Serine/threonine-protein kinase RAD53

1

10

High-throughput

0.618

High

425619

AKL1
Serine/threonine-protein kinase AKL1

1

7

High-throughput

0.618

High

425620

SRO77
Lethal(2) giant larvae protein homolog SRO77

2

1

High-throughput

0.590

High

425569

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

Small-scale

0.586

High

425599

SIS1
Protein SIS1

2

1

High-throughput

0.571

High

425613

HSP78
Heat shock protein 78, mitochondrial

2

1

High-throughput

0.571

High

425589

IRA2
Inhibitory regulator protein IRA2

1

5

Small-scale

0.561

High

425591

MYO2
Myosin-2

1

6

Small-scale

0.561

High

425583

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.559

High

425602

TF2B
Transcription initiation factor IIB

2

0

High-throughput

0.551

High

425615

MSN4
Zinc finger protein MSN4

1

1

High-throughput

0.541

High

425647

RNT1
Ribonuclease 3

1

1

High-throughput

0.541

High

342818

ENO2
Enolase 2

1

0

Small-scale

0.537

High

425592

HSP60
Heat shock protein 60, mitochondrial

1

0

Small-scale

0.537

High

425617

YPT53
GTP-binding protein YPT53

1

10

High-throughput

0.536

High

425645

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

4

High-throughput

0.536

High

425646

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.536

High

425641

SOK2
Protein SOK2

1

0

High-throughput

0.518

High

425656

TIP41
Type 2A phosphatase activator TIP41

1

0

High-throughput

0.518

High

425623

DHE5
NADP-specific glutamate dehydrogenase 2

1

1

High-throughput

0.515

High

425624

RV167
Reduced viability upon starvation protein 167

1

1

High-throughput

0.515

High

425648

SKI8
Antiviral protein SKI8

1

3

High-throughput

0.515

High

425259

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

425625

PP2C2
Protein phosphatase 2C homolog 2

1

0

High-throughput

0.513

High

425627

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.513

High

425598

PTP1
Tyrosine-protein phosphatase 1

1

10

Small-scale

0.501

High

425640

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

1

High-throughput

0.494

High

425603

EF1G1
Elongation factor 1-gamma 1

1

0

High-throughput

0.493

High

425662

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.493

High

425659

ATG5
Autophagy protein 5

1

0

High-throughput

0.486

High

425570

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

1

11

Small-scale

0.481

High

425639

ZDS1
Protein ZDS1

1

4

Small-scale

0.481

High

365586

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

417550

PHSG
Glycogen phosphorylase

1

4

Small-scale

0.479

High

424275

PYR1
Multifunctional protein URA2

1

4

Small-scale

0.479

High

425571

RL20B
Large ribosomal subunit protein eL20B

1

2

Small-scale

0.479

High

425575

RL4A
Large ribosomal subunit protein uL4A

1

2

Small-scale

0.479

High

425576

PYC1
Pyruvate carboxylase 1

1

4

Small-scale

0.479

High

425585

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

2

Small-scale

0.479

High

425600

SPT5
Transcription elongation factor SPT5

1

1

Small-scale

0.479

High

425604

HS104
Heat shock protein 104

1

1

Small-scale

0.479

High

425606

PYC2
Pyruvate carboxylase 2

1

4

Small-scale

0.479

High

425618

GBLP
Small ribosomal subunit protein RACK1

1

7

Small-scale

0.479

High

425621

FKS1
1,3-beta-glucan synthase component FKS1

1

1

Small-scale

0.479

High

425628

SYA
Alanine--tRNA ligase, mitochondrial

1

1

Small-scale

0.479

High

425632

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

425638

RL4B
Large ribosomal subunit protein uL4B

1

2

Small-scale

0.479

High

425643

CRZ1
Transcriptional regulator CRZ1

1

1

Small-scale

0.479

High

425644

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

2

Small-scale

0.479

High

425657

RL7B
Large ribosomal subunit protein uL30B

1

1

Small-scale

0.479

High

425661

RL13A
Large ribosomal subunit protein eL13A

1

1

Small-scale

0.479

High

334580

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

Small-scale

0.458

High

339966

KPYK1
Pyruvate kinase 1

1

0

Small-scale

0.458

High

340581

PGK
Phosphoglycerate kinase

1

0

Small-scale

0.458

High

375212

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

410730

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

Small-scale

0.458

High

410855

PDC1
Pyruvate decarboxylase isozyme 1

1

0

Small-scale

0.458

High

421541

FAS1
Fatty acid synthase subunit beta

1

0

Small-scale

0.458

High

425568

GAL7
Galactose-1-phosphate uridylyltransferase

1

0

Small-scale

0.458

High

425572

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.458

High

425578

ALF
Fructose-bisphosphate aldolase

1

0

Small-scale

0.458

High

425582

VATB
V-type proton ATPase subunit B

1

0

Small-scale

0.458

High

425588

FAS2
Fatty acid synthase subunit alpha

1

0

Small-scale

0.458

High

425590

ACON
Aconitate hydratase, mitochondrial

1

0

Small-scale

0.458

High

425601

ACEA
Isocitrate lyase

1

0

Small-scale

0.458

High

425605

EF2
Elongation factor 2

1

0

Small-scale

0.458

High

425607

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

425609

GLGB
1,4-alpha-glucan-branching enzyme

1

0

Small-scale

0.458

High

425611

RSSA1
Small ribosomal subunit protein uS2A

1

0

Small-scale

0.458

High

425612

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

425614

RS3A1
Small ribosomal subunit protein eS1A

1

0

Small-scale

0.458

High

425616

TSA1
Peroxiredoxin TSA1

1

0

Small-scale

0.458

High

425622

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

425629

AXL1
Putative protease AXL1

1

0

High-throughput

0.458

High

425631

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

0

Small-scale

0.458

High

425636

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

425637

JHD2
Histone demethylase JHD2

1

0

Small-scale

0.458

High

425650

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

425651

NEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.458

High

425652

GDE
Glycogen debranching enzyme

1

0

Small-scale

0.458

High

425654

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

425655

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

425660

WHI5
G1-specific transcriptional repressor WHI5

1

0

High-throughput

0.458

High

425574

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

425577

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

425584

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.445

High

425608

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

425626

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

425587

ADT2
ADP,ATP carrier protein 2

1

4

Small-scale

0.437

High

425633

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

2

Small-scale

0.437

High

425642

COPA
Coatomer subunit alpha

1

1

Small-scale

0.437

High

425653

AP3D
AP-3 complex subunit delta

1

5

High-throughput

0.437

High

425593

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.426

High

425630

CDC1
Cell division control protein 1

1

0

Small-scale

0.249

Low

425634

PRY1
Protein PRY1

1

0

High-throughput

0.249

Low

425579

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

425635

GPI14
GPI mannosyltransferase 1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024