HitPredict

Interactor 1: HLAA (P04439)
HLA class I histocompatibility antigen, A alpha chain (Human leukocyte antigen A) (HLA-A)
Gene: HLA-A

Interactor 2: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 1114
+	Hs
		382306 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		FGFR2_HUMAN (501-1065): 3.92e-155: 484: 33.11
+	Hs
		382280 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		337747 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24
+	Hs
		382259 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		337728 HLAH_HUMAN (1-362): 7.94e-161: 456: 85.64		EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24
+	Hs
		382308 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89
+	Hs
		337829 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24
+	Hs
		169158 HLAB_HUMAN (1-362): 3.05e-157: 447: 85.64		MUSK_HUMAN (396-1018): 1.21e-135: 434: 25.28
+	Hs
		169162 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		MUSK_HUMAN (396-1018): 1.21e-135: 434: 25.28
+	Hs
		382433 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19
+	Hs
		488237 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19
+	Hs
		382329 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25
+	Hs
		382331 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		FLT3_HUMAN (714-1014): 2.21e-72: 262: 40.00
+	Hs
		673955 HLAF_HUMAN (4-348): 3.64e-141: 406: 80.29		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19
+	Hs
		488144 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		FLT3_HUMAN (714-1014): 2.21e-72: 262: 40.00