HitPredict

Interactor 1: HLAA (P04439)
HLA class I histocompatibility antigen, A alpha chain (Human leukocyte antigen A) (HLA-A)
Gene: HLA-A

Interactor 2: TYRO3 (Q06418)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~fn3
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0009986 - cell surface
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 890
+	Hs
		382450 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		EPHAA_HUMAN (203-842): 1.14e-129: 416: 23.35
+	Hs
		533134 HLAE_HUMAN (20-357): 5.1e-143: 411: 78.99		EPHB4_HUMAN (117-823): 1.31e-155: 483: 19.59
+	Rn
		544828 Q31255_RAT (4-364): 1.77e-156: 445: 64.38		INSR_RAT (232-788): 7.04e-127: 416: 27.65
+	Hs
		488252 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		EPHAA_HUMAN (203-842): 1.14e-129: 416: 23.35
+	Rn
		64757 A7LNF8_RAT (25-329): 1.07e-131: 380: 66.89		INSR_RAT (232-788): 7.04e-127: 416: 27.65
+	Hs
		382272 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		MET_HUMAN (495-790): 3.89e-65: 240: 41.67
+	Hs
		382269 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		382263 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		INSR_HUMAN (292-790): 2.17e-60: 226: 31.15
+	Hs
		382268 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		RET_HUMAN (514-790): 1.89e-55: 210: 39.93
+	Hs
		382324 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		RYK_HUMAN (503-782): 8.78e-55: 202: 37.50
+	Hs
		382306 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		FGFR2_HUMAN (2-234): 1.07e-43: 172: 13.68
+	Hs
		441407 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		MET_HUMAN (495-790): 3.89e-65: 240: 41.67
+	Hs
		435507 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		382280 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		FGFR1_HUMAN (6-230): 2.63e-19: 95.6: 18.22
+	Hs
		169158 HLAB_HUMAN (1-362): 3.05e-157: 447: 85.64		MUSK_HUMAN (42-257): 7.52e-27: 119: 16.59
+	Hs
		169162 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		MUSK_HUMAN (42-257): 7.52e-27: 119: 16.59