HitPredict

Interactor 1: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Interactor 2: IGFL3 (Q6UXB1)
Insulin growth factor-like family member 3
Gene: IGFL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 2471 Hs			1 125
+	Hs
		804271 NOTC1_HUMAN (2-1107): 2.62e-145: 509: 33.88		IGFL3_HUMAN (1-125): 6.23e-59: 179: 100.00
+	Hs
		1166403 JAG2_HUMAN (2-501): 6.2e-66: 249: 33.21		IGFL3_HUMAN (1-125): 6.23e-59: 179: 100.00
+	Hs
		724377 FBN2_HUMAN (474-1671): 8.72e-37: 155: 16.92		IGFL3_HUMAN (1-125): 6.23e-59: 179: 100.00
+	Hs
		1166401 NOTC3_HUMAN (1931-2465): 6.29e-11: 70.7: 16.82		IGFL3_HUMAN (1-125): 6.23e-59: 179: 100.00