HitPredict

Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Interactor 2: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 152
+	Hs
		338223 EGFR_HUMAN (16-1253): 0: 1070: 48.40		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Zm
		41149 B4G007_MAIZE (445-1027): 1.51e-137: 434: 16.16		A0A1D6NG29_MAIZE (2-148): 7.04e-78: 229: 69.94
+	Hs
		896558 EPHA6_HUMAN (638-1023): 7.48e-116: 388: 29.24		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		435592 IGF1R_HUMAN (337-633): 4.59e-20: 99.1: 22.92		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00