HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: F1711 (Q5VUB5)
Protein FAM171A1 (Astroprincin) (APCN)
Gene: FAM171A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25921289, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 796 Hs			1 890
+	Hs
		508056 FGFR1_HUMAN (195-794): 0: 545: 26.34		F1711_HUMAN (1-890): 0: 1330: 100.00
+	Hs
		1083855 NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72		F1711_HUMAN (1-890): 0: 1330: 100.00
+	Hs
		1081506 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		F1711_HUMAN (1-890): 0: 1330: 100.00
+	Hs
		608007 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		F1711_HUMAN (1-890): 0: 1330: 100.00
+	Hs
		665405 EPHA3_HUMAN (262-788): 8.75e-112: 365: 26.64		F1711_HUMAN (1-890): 0: 1330: 100.00
+	Hs
		872449 EPHA5_HUMAN (409-788): 2.48e-111: 365: 30.36		F1711_HUMAN (1-890): 0: 1330: 100.00
+	Hs
		968311 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		F1711_HUMAN (1-890): 0: 1330: 100.00
+	Hs
		68124 NTRK1_HUMAN (1-796): 0: 621: 100.00		F1712_HUMAN (32-890): 0: 916: 38.37
+	Mm
		546294 NTRK2_MOUSE (12-796): 2.75e-174: 524: 47.32		F171B_MOUSE (27-888): 0: 980: 32.12
+	Hs
		1083858 NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72		F171B_HUMAN (27-888): 0: 967: 31.41
+	Hs
		68129 FGFR1_HUMAN (195-794): 0: 545: 26.34		F1712_HUMAN (32-890): 0: 916: 38.37
+	Hs
		601533 FGFR2_HUMAN (87-794): 5.67e-159: 484: 22.55		F171B_HUMAN (27-888): 0: 967: 31.41
+	Hs
		68174 NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72		F1712_HUMAN (32-890): 0: 916: 38.37
+	Mm
		1062026 PTK7_MOUSE (201-781): 5.12e-148: 462: 27.17		F171B_MOUSE (27-888): 0: 980: 32.12
+	Hs
		68172 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		F1712_HUMAN (32-890): 0: 916: 38.37
+	Hs
		68137 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		F1712_HUMAN (32-890): 0: 916: 38.37
+	Mm
		56856 PTK7_MOUSE (201-781): 5.12e-148: 462: 27.17		F1712_MOUSE (32-890): 0: 912: 39.63
+	Hs
		68141 EPHA3_HUMAN (262-788): 8.75e-112: 365: 26.64		F1712_HUMAN (32-890): 0: 916: 38.37
+	Hs
		68151 EPHA5_HUMAN (409-788): 2.48e-111: 365: 30.36		F1712_HUMAN (32-890): 0: 916: 38.37
+	Hs
		68164 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		F1712_HUMAN (32-890): 0: 916: 38.37