HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: TONSL (Q96HA7)
Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)
Gene: TONSL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_6~LRR_8
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 796 Hs			1 1378
+	Hs
		385487 NTRK1_HUMAN (1-796): 0: 621: 100.00		TANC1_HUMAN (73-1074): 3.83e-65: 246: 11.04
+	Hs
		384666 NTRK1_HUMAN (1-796): 0: 621: 100.00		ANK2_HUMAN (101-617): 1.81e-51: 202: 16.57
+	Hs
		507831 FGFR1_HUMAN (195-794): 0: 545: 26.34		ANK1_HUMAN (11-791): 3.81e-70: 262: 13.88
+	Hs
		508185 FGFR1_HUMAN (195-794): 0: 545: 26.34		TANC1_HUMAN (73-1074): 3.83e-65: 246: 11.04
+	Hs
		608115 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		TANC1_HUMAN (73-1074): 3.83e-65: 246: 11.04
+	Hs
		507954 FGFR1_HUMAN (195-794): 0: 545: 26.34		ANK2_HUMAN (101-617): 1.81e-51: 202: 16.57
+	Hs
		507971 FGFR1_HUMAN (195-794): 0: 545: 26.34		ANK3_HUMAN (120-617): 7.94e-49: 194: 16.63
+	Hs
		384187 NTRK1_HUMAN (1-796): 0: 621: 100.00		RINI_HUMAN (1008-1220): 6.76e-22: 102: 17.76
+	Hs
		1021409 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		ANK3_HUMAN (120-617): 7.94e-49: 194: 16.63
+	Hs
		385118 NTRK1_HUMAN (1-796): 0: 621: 100.00		GPSM1_HUMAN (2-178): 7.72e-20: 98: 19.21
+	Hs
		385317 NTRK1_HUMAN (1-796): 0: 621: 100.00		TTC28_HUMAN (7-522): 3.17e-19: 96.8: 15.50
+	Hs
		257545 NTRK1_HUMAN (1-796): 0: 621: 100.00		ANR17_HUMAN (14-752): 1.73e-18: 94.5: 13.46
+	Hs
		174540 NTRK1_HUMAN (1-796): 0: 621: 100.00		OGT1_HUMAN (2-241): 3.04e-15: 83.3: 15.29
+	Hs
		474791 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		POTEI_HUMAN (339-1051): 1.31e-52: 204: 12.04
+	Hs
		608032 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		GPSM1_HUMAN (2-178): 7.72e-20: 98: 19.21
+	At
		1338064 TMK3_ARATH (60-784): 3.16e-145: 452: 19.98		RGI1_ARATH (838-1250): 1.1e-31: 137: 14.18
+	Hs
		434183 RET_HUMAN (391-794): 3.5e-114: 374: 30.44		ANK3_HUMAN (120-617): 7.94e-49: 194: 16.63
+	Hs
		968475 ROR2_HUMAN (515-783): 2.79e-66: 239: 43.91		TANC1_HUMAN (73-1074): 3.83e-65: 246: 11.04
+	Hs
		411283 INSR_HUMAN (493-777): 3e-68: 248: 42.62		POTEJ_HUMAN (414-1051): 4.1e-52: 202: 12.25
+	At
		84588 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		RGI3_ARATH (776-1175): 2.27e-13: 77.5: 10.32