HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: GHC1 (Q9H936)
Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22)
Gene: SLC25A22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.50	0.543

Property	Details
Experiments	25921289, 35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 323
+	Hs
		1081606 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		GHC1_HUMAN (1-323): 5.73e-99: 296: 100.00
+	Hs
		384086 NTRK1_HUMAN (1-796): 0: 621: 100.00		ADT2_HUMAN (101-322): 5.12e-38: 138: 18.50
+	Hs
		384544 NTRK1_HUMAN (1-796): 0: 621: 100.00		TXTP_HUMAN (5-306): 1.85e-24: 102: 27.10
+	Hs
		385684 NTRK1_HUMAN (1-796): 0: 621: 100.00		S2513_HUMAN (229-323): 2.62e-21: 96.5: 32.65
+	Hs
		384178 NTRK1_HUMAN (1-796): 0: 621: 100.00		ADT3_HUMAN (224-322): 3.75e-13: 70.7: 25.49
+	Hs
		397400 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		ADT2_HUMAN (101-322): 5.12e-38: 138: 18.50
+	Hs
		507816 FGFR1_HUMAN (195-794): 0: 545: 26.34		ADT3_HUMAN (224-322): 3.75e-13: 70.7: 25.49
+	Hs
		518252 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		ADT3_HUMAN (224-322): 3.75e-13: 70.7: 25.49
+	Hs
		411496 INSR_HUMAN (493-777): 3e-68: 248: 42.62		GHC1_HUMAN (1-323): 5.73e-99: 296: 100.00
+	Hs
		397233 IGF1R_HUMAN (493-777): 6.97e-71: 255: 42.61		ADT2_HUMAN (101-322): 5.12e-38: 138: 18.50
+	Hs
		397405 DDR2_HUMAN (499-781): 3.37e-72: 254: 44.55		ADT2_HUMAN (101-322): 5.12e-38: 138: 18.50
+	Hs
		397354 DDR1_HUMAN (507-778): 1.77e-67: 242: 45.49		ADT2_HUMAN (101-322): 5.12e-38: 138: 18.50
+	Hs
		858264 DDR2_HUMAN (499-781): 3.37e-72: 254: 44.55		TXTP_HUMAN (5-306): 1.85e-24: 102: 27.10
+	Hs
		1088154 DDR2_HUMAN (499-781): 3.37e-72: 254: 44.55		S2513_HUMAN (229-323): 2.62e-21: 96.5: 32.65
+	Hs
		858235 ROR2_HUMAN (515-783): 2.79e-66: 239: 43.91		TXTP_HUMAN (5-306): 1.85e-24: 102: 27.10
+	Rn
		544923 INSR_RAT (493-777): 7.31e-66: 241: 41.95		Q9EP88_RAT (218-317): 2.29e-17: 83: 25.00