HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30554943, 35575683
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 726
+	Hs
		259281 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259827 LMNB2_HUMAN (21-581): 2.95e-51: 189: 52.59		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259435 LMNB1_HUMAN (21-581): 1.2e-49: 184: 54.45		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259329 VIME_HUMAN (27-389): 3.96e-31: 129: 28.93		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		386356 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		BRPF3_HUMAN (20-316): 1.15e-29: 128: 14.29
+	Hs
		386030 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		PHIP_HUMAN (5-702): 1.66e-17: 89.5: 11.03
+	Mm
		97887 Q3U6S1_MOUSE (27-394): 8.17e-32: 130: 29.35		CECR2_MOUSE (144-559): 8.89e-31: 132: 13.92