Interactor 1: CPNS1 (P04632)
Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)
Gene: CAPNS1

Interactor 2: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.724

The method score is based on:

Property Details
Experiments 26496610, 28514442, 33961781, 36964131, 19712109
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, enzyme linked immunosorbent assay, protease assay
Interaction Type physical association, association, cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004198 - calcium-dependent cysteine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
and 5 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 268
Hs

1 714
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+ Dm
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Last updated: 15 Jul 2024