HitPredict

Interactor 1: CPNS1 (P04632)
Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)
Gene: CAPNS1

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	31324722, 17110338, 26618866
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 268 Hs			1 1480
+	Hs
		427833 CAN1_HUMAN (65-268): 6.89e-57: 195: 44.88		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		259687 PDCD6_HUMAN (103-265): 2.75e-55: 178: 27.27		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528495 CAN2_HUMAN (65-262): 3.03e-50: 177: 43.94		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		484052 CALM3_HUMAN (56-171): 1.29e-16: 76.5: 20.16		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528591 CALL3_HUMAN (56-167): 2.07e-15: 73.4: 20.00		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529820 CALL5_HUMAN (172-258): 9.88e-10: 57.6: 31.52		CFTR_HUMAN (1-1480): 0: 1031: 100.00