Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 15964625, 15310764, 15144954, 16376884, 12080348, 31152661, 32807901, 15082766, 16740634, 23443559
Identification Methods affinity chromatography technology, pull down, coimmunoprecipitation, anti bait coimmunoprecipitation, cross-linking study, surface plasmon resonance
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001046 - core promoter sequence-specific DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 11 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 393
Hs

1 294
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024