HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	16169070, 38580884
Identification Methods	two hybrid, proximity labelling technology, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0051726 - regulation of cell cycle GO:2000378 - negative regulation of reactive oxygen species metabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1271
+	Hs
		386635 P53_HUMAN (1-393): 0: 619: 100.00		ABR_HUMAN (419-1271): 0: 567: 66.47
+	Hs
		386972 P53_HUMAN (1-393): 0: 619: 100.00		FGD6_HUMAN (93-969): 1.47e-86: 311: 14.15
+	Hs
		387275 P53_HUMAN (1-393): 0: 619: 100.00		ARHGQ_HUMAN (79-816): 3.76e-86: 302: 16.02
+	Hs
		387581 P53_HUMAN (1-393): 0: 619: 100.00		ARHG4_HUMAN (293-889): 6.61e-76: 268: 13.11
+	Hs
		386637 P53_HUMAN (1-393): 0: 619: 100.00		RHG05_HUMAN (900-1263): 2.31e-71: 264: 21.92
+	Hs
		387328 P53_HUMAN (1-393): 0: 619: 100.00		ARHGH_HUMAN (454-761): 1.15e-70: 263: 28.41
+	Hs
		387531 P53_HUMAN (1-393): 0: 619: 100.00		ECT2_HUMAN (335-923): 3.96e-71: 259: 17.07
+	Hs
		299229 P53_HUMAN (1-393): 0: 619: 100.00		FARP2_HUMAN (356-812): 1.08e-68: 253: 18.26