HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27248496, 31353912
Identification Methods	affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 626
+	Hs
		634642 LMNB1_HUMAN (21-581): 1.2e-49: 184: 54.45		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		474993 VIME_HUMAN (27-389): 3.96e-31: 129: 28.93		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		407268 K2C6B_HUMAN (24-407): 4.84e-115: 357: 23.51		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		407329 K2C6B_HUMAN (24-407): 4.84e-115: 357: 23.51		SNR40_HUMAN (440-625): 1.14e-33: 134: 11.83
+	Hs
		386057 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		FBXW7_HUMAN (247-571): 4.45e-61: 217: 13.72
+	Hs
		386072 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		SNR40_HUMAN (440-625): 1.14e-33: 134: 11.83
+	Hs
		385680 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		RBBP4_HUMAN (233-477): 2.85e-19: 92.6: 14.55
+	Hs
		964870 LMNB2_HUMAN (21-581): 2.95e-51: 189: 52.59		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		634390 LMNB1_HUMAN (21-581): 1.2e-49: 184: 54.45		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		570412 GFAP_HUMAN (27-427): 1.13e-28: 121: 27.43		ERCC8_HUMAN (305-532): 1.36e-57: 200: 19.92
+	Hs
		634574 LMNB1_HUMAN (21-581): 1.2e-49: 184: 54.45		SNR40_HUMAN (440-625): 1.14e-33: 134: 11.83
+	Hs
		570546 GFAP_HUMAN (27-427): 1.13e-28: 121: 27.43		SNR40_HUMAN (440-625): 1.14e-33: 134: 11.83
+	Hs
		1294688 K2C73_HUMAN (226-558): 7.25e-09: 60.6: 11.63		POC1A_HUMAN (391-623): 3.95e-49: 178: 12.45