HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: HS105 (Q92598)
Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein) (Heat shock protein family H member 1)
Gene: HSPH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	32807901, 35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 858
+	Hs
		320791 P53_HUMAN (1-393): 0: 619: 100.00		HS74L_HUMAN (1-858): 0: 953: 57.46
+	Hs
		386200 P53_HUMAN (1-393): 0: 619: 100.00		HSP74_HUMAN (1-858): 0: 917: 60.98
+	Rn
		291978 P53_RAT (1-393): 0: 572: 77.02		HSP74_RAT (1-858): 0: 914: 61.28
+	Hs
		175831 P73_HUMAN (13-362): 2.35e-166: 481: 39.74		HSP74_HUMAN (1-858): 0: 917: 60.98
+	Hs
		714407 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		HSP74_HUMAN (1-858): 0: 917: 60.98
+	Hs
		385979 P53_HUMAN (1-393): 0: 619: 100.00		HSP7C_HUMAN (489-709): 2.48e-32: 135: 11.26
+	Hs
		386199 P53_HUMAN (1-393): 0: 619: 100.00		HS71L_HUMAN (586-716): 7.63e-31: 131: 19.70
+	Hs
		386050 P53_HUMAN (1-393): 0: 619: 100.00		HSP76_HUMAN (604-707): 8.59e-27: 118: 22.86
+	Mm
		356821 P53_MOUSE (1-393): 0: 589: 77.35		HS71L_MOUSE (586-716): 1e-31: 134: 18.94
+	Mm
		356822 P53_MOUSE (1-393): 0: 589: 77.35		HS71B_MOUSE (586-704): 1.63e-24: 111: 21.67
+	Hs
		1093060 Q1MSW8_HUMAN (1-331): 0: 517: 99.70		Q53FC7_HUMAN (604-707): 1.8e-26: 117: 21.91