Protein: SAA1
Serum amyloid A-1 protein (SAA) [Cleaved into: Amyloid protein A (Amyloid fibril protein AA); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(2-103); Serum amyloid protein A(2-102); Serum amyloid protein A(4-101)]

Gene: SAA1
Organism: Homo sapiens
Interactions: 51
UniProt ID: P0DJI8

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0001819 - positive regulation of cytokine production
GO:0005576 - extracellular region
GO:0005881 - cytoplasmic microtubule
GO:0006953 - acute-phase response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

515873

SAA2
Serum amyloid A-2 protein

3

2

High-throughput

0.839

High

515875

SAA4
Serum amyloid A-4 protein

1

2

High-throughput

0.618

High

515882

SAFB2
Scaffold attachment factor B2

1

2

High-throughput

0.536

High

515877

PRC2A
Protein PRRC2A

1

0

High-throughput

0.513

High

515884

SAFB1
Scaffold attachment factor B1

1

2

High-throughput

0.489

High

515886

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

1

High-throughput

0.489

High

515894

PHF3
PHD finger protein 3

1

1

High-throughput

0.489

High

515895

RMXL1
RNA binding motif protein, X-linked-like-1

1

1

High-throughput

0.489

High

515902

DIDO1
Death-inducer obliterator 1

1

2

High-throughput

0.489

High

515906

SLTM
SAFB-like transcription modulator

1

2

High-throughput

0.489

High

515900

SELS
Selenoprotein S

1

0

Small-scale

0.480

High

387212

APOA1
Apolipoprotein A-I

1

3

High-throughput

0.479

High

387365

APOE
Apolipoprotein E

1

3

High-throughput

0.479

High

387502

APOA2
Apolipoprotein A-II

1

2

High-throughput

0.479

High

515876

GLP1R
Glucagon-like peptide 1 receptor

1

0

Small-scale

0.460

High

407830

SEMG1
Semenogelin-1

1

1

High-throughput

0.445

High

515880

SEMG2
Semenogelin-2

1

1

High-throughput

0.445

High

277260

PITX3
Pituitary homeobox 3

1

1

Small-scale

0.437

High

51031

PKHG3
Pleckstrin homology domain-containing family G member 3

1

0

High-throughput

0.279

Low

215489

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.279

Low

515874

UBF1
Nucleolar transcription factor 1

1

0

High-throughput

0.279

Low

515878

YLPM1
YLP motif-containing protein 1

1

0

High-throughput

0.279

Low

515883

PDIA5
Protein disulfide-isomerase A5

1

0

High-throughput

0.279

Low

515885

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.279

Low

515887

MPRIP
Myosin phosphatase Rho-interacting protein

1

0

High-throughput

0.279

Low

515889

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.279

Low

515890

PPHLN
Periphilin-1

1

0

High-throughput

0.279

Low

515891

RP9
Retinitis pigmentosa 9 protein

1

0

High-throughput

0.279

Low

515892

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.279

Low

515893

CATIN
Splicing factor Cactin

1

0

High-throughput

0.279

Low

515896

RRP36
Ribosomal RNA processing protein 36 homolog

1

0

High-throughput

0.279

Low

515897

LRCH3
DISP complex protein LRCH3

1

0

High-throughput

0.279

Low

515898

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.279

Low

515901

NUD12
NAD-capped RNA hydrolase NUDT12

1

0

High-throughput

0.279

Low

515903

WDR33
pre-mRNA 3' end processing protein WDR33

1

0

High-throughput

0.279

Low

515904

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

0

High-throughput

0.279

Low

515905

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.279

Low

515907

CWC25
Pre-mRNA-splicing factor CWC25 homolog

1

0

High-throughput

0.279

Low

515908

CDK12
Cyclin-dependent kinase 12

1

0

High-throughput

0.279

Low

515909

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.279

Low

515910

RAI14
Ankycorbin

1

0

High-throughput

0.279

Low

515911

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.279

Low

515912

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.279

Low

515913

NEB1
Neurabin-1

1

0

High-throughput

0.279

Low

515914

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

0

High-throughput

0.279

Low

515915

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.279

Low

515916

KC1G3
Casein kinase I isoform gamma-3

1

0

High-throughput

0.279

Low

515899

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.251

Low

515879

CNN1
Calponin-1

1

0

High-throughput

0.249

Low

515881

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.249

Low

515888

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025