Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.765

The method score is based on:

Property Details
Experiments 25144556, 27807478, 27775703, 32097779, 18223694, 35140242, 34591612, 38580884, 17666403, 21268072, 25543083, 26330542, 29953728, 30911017, 20618441, 15911628, 22254155, 15001357, 23134341
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002931 - response to ischemia
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 8 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 393
Hs

1 303
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024