Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: ING4 (Q9UNL4)
Inhibitor of growth protein 4 (p29ING4)
Gene: ING4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 23967213, 12750254, 17954561, 15882981, 21177815, 31754246, 18775696, 20053357, 21454715, 15251430
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription
GO:0008285 - negative regulation of cell population proliferation
and 4 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 393
Hs

1 249
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024