Interactor 1: TOP1 (P04786)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) (Maintenance of killer protein 1)
Gene: TOP1

Interactor 2: TOF1 (P53840)
Topoisomerase 1-associated factor 1
Gene: TOF1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.55 0.593

The method score is based on:

Property Details
Experiments 10028183, 31805522
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006260 - DNA replication
GO:0031298 - replication fork protection complex
Homologous interactions 0

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Last updated: 15 Jul 2024