Protein: CUX1
Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP/Cux p200) (Homeobox protein cux-1) [Cleaved into: CDP/Cux p110]

Gene: CUX1
Organism: Homo sapiens
Interactions: 204
UniProt ID: P39880

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

814787

SATB1
DNA-binding protein SATB1

1

7

Small-scale

0.724

High

814764

SOX2
Transcription factor SOX-2

5

20

Small-scale

0.709

High

814775

MAX
Protein max

1

11

High-throughput

0.698

High

155709

CUX2
Homeobox protein cut-like 2

1

20

High-throughput

0.691

High

225945

STX6
Syntaxin-6

4

4

High-throughput

0.686

High

814761

MAGAA
Melanoma-associated antigen 10

4

12

High-throughput

0.683

High

814781

H31
Histone H3.1

3

9

High-throughput

0.640

High

814818

S39A4
Zinc transporter ZIP4

4

12

High-throughput

0.623

High

181489

TBXT
T-box transcription factor T

1

8

High-throughput

0.618

High

224947

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.618

High

226518

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.618

High

549293

SRF
Serum response factor

1

4

High-throughput

0.618

High

581627

MYOD1
Myoblast determination protein 1

1

3

High-throughput

0.618

High

685118

PAX6
Paired box protein Pax-6

1

19

High-throughput

0.618

High

725214

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.618

High

814758

CUX1
Homeobox protein cut-like 1

1

17

High-throughput

0.618

High

814769

LHX2
LIM/homeobox protein Lhx2

1

17

High-throughput

0.618

High

814792

HME1
Homeobox protein engrailed-1

1

11

High-throughput

0.618

High

814880

LHX3
LIM/homeobox protein Lhx3

1

17

High-throughput

0.618

High

540338

LAMP1
Lysosome-associated membrane glycoprotein 1

2

8

High-throughput

0.611

High

814837

EXT2
Exostosin-2

2

2

High-throughput

0.611

High

380410

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

3

3

High-throughput

0.599

High

814852

WDR83
WD repeat domain-containing protein 83

3

14

High-throughput

0.599

High

814814

S39AC
Zinc transporter ZIP12

3

12

High-throughput

0.593

High

814844

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

11

Small-scale

0.586

High

442623

RB
Retinoblastoma-associated protein

1

3

Small-scale

0.586

High

814777

H4
Histone H4

2

10

High-throughput

0.584

High

814807

HDAC1
Histone deacetylase 1

2

20

High-throughput

0.584

High

814810

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

219282

B4GA1
Beta-1,4-glucuronyltransferase 1

2

1

High-throughput

0.571

High

814877

GPC5B
G-protein coupled receptor family C group 5 member B

2

4

High-throughput

0.571

High

814791

TLE4
Transducin-like enhancer protein 4

1

20

Small-scale

0.561

High

814835

CBP
CREB-binding protein

1

20

Small-scale

0.561

High

179828

BET1
BET1 homolog

2

5

High-throughput

0.558

High

814812

RAB30
Ras-related protein Rab-30

2

14

High-throughput

0.558

High

814762

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

2

2

High-throughput

0.549

High

138457

BIN1
Myc box-dependent-interacting protein 1

1

4

High-throughput

0.541

High

316262

RECQ5
ATP-dependent DNA helicase Q5

1

15

High-throughput

0.541

High

573770

CCNB1
G2/mitotic-specific cyclin-B1

1

2

Small-scale

0.536

High

133090

FOXE1
Forkhead box protein E1

1

20

High-throughput

0.536

High

186840

FOXN1
Forkhead box protein N1

1

20

High-throughput

0.536

High

340840

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

10

High-throughput

0.536

High

349388

TSN15
Tetraspanin-15

1

9

High-throughput

0.536

High

571566

IRF2
Interferon regulatory factor 2

1

3

High-throughput

0.536

High

789066

NUP62
Nuclear pore glycoprotein p62

1

2

High-throughput

0.536

High

814773

FOXG1
Forkhead box protein G1

1

20

High-throughput

0.536

High

814786

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.536

High

814793

SUH
Recombining binding protein suppressor of hairless

1

1

High-throughput

0.536

High

814794

FMR1
Fragile X messenger ribonucleoprotein 1

1

6

High-throughput

0.536

High

814799

FOXO1
Forkhead box protein O1

1

20

High-throughput

0.536

High

814843

Z512B
Zinc finger protein 512B

1

19

High-throughput

0.536

High

814854

SSBP3
Single-stranded DNA-binding protein 3

1

15

High-throughput

0.536

High

814857

FOXQ1
Forkhead box protein Q1

1

20

High-throughput

0.536

High

814865

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.536

High

814870

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.536

High

814879

FOXJ2
Forkhead box protein J2

1

20

High-throughput

0.536

High

814882

FOXD3
Forkhead box protein D3

1

20

High-throughput

0.536

High

814893

TACC3
Transforming acidic coiled-coil-containing protein 3

1

20

High-throughput

0.536

High

814796

TNR9
Tumor necrosis factor receptor superfamily member 9

2

7

High-throughput

0.521

High

814823

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

2

10

High-throughput

0.521

High

814849

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.518

High

437113

K2C8
Keratin, type II cytoskeletal 8

1

16

High-throughput

0.515

High

814875

SPS2L
SPATS2-like protein

1

0

High-throughput

0.513

High

443241

CDK1
Cyclin-dependent kinase 1

1

13

Small-scale

0.501

High

814770

CDK7
Cyclin-dependent kinase 7

1

17

Small-scale

0.501

High

814776

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.501

High

814783

CCNA1
Cyclin-A1

1

2

Small-scale

0.501

High

814836

KAT2B
Histone acetyltransferase KAT2B

1

14

Small-scale

0.501

High

173876

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

5

High-throughput

0.489

High

328359

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

1

High-throughput

0.489

High

689937

IL3RA
Interleukin-3 receptor subunit alpha

1

1

High-throughput

0.489

High

814774

CXCR4
C-X-C chemokine receptor type 4

1

8

High-throughput

0.489

High

814811

P2RY6
P2Y purinoceptor 6

1

13

High-throughput

0.489

High

814813

C3AR
C3a anaphylatoxin chemotactic receptor

1

6

High-throughput

0.489

High

814827

SYCE1
Synaptonemal complex central element protein 1

1

2

High-throughput

0.489

High

814838

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

5

High-throughput

0.489

High

814850

KXDL1
KxDL motif-containing protein 1

1

1

High-throughput

0.489

High

814860

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

2

High-throughput

0.489

High

814866

CSTN2
Calsyntenin-2

1

1

High-throughput

0.489

High

814803

CAF1B
Chromatin assembly factor 1 subunit B

1

13

High-throughput

0.481

High

128822

MEN1
Menin

1

4

High-throughput

0.479

High

141822

ACKR2
Atypical chemokine receptor 2

1

9

High-throughput

0.479

High

157039

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.479

High

216883

KLF4
Krueppel-like factor 4

1

15

High-throughput

0.479

High

239922

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.479

High

246458

KDM1A
Lysine-specific histone demethylase 1A

1

7

High-throughput

0.479

High

327184

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

373810

RASN
GTPase NRas

1

20

High-throughput

0.479

High

403885

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

473833

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

474527

VIME
Vimentin

1

20

High-throughput

0.479

High

487037

PARP1
Poly [ADP-ribose] polymerase 1

1

8

High-throughput

0.479

High

507628

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.479

High

519345

MYB
Transcriptional activator Myb

1

5

High-throughput

0.479

High

519804

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

606354

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

629615

BTF3
Transcription factor BTF3

1

7

High-throughput

0.479

High

662385

GATA2
Endothelial transcription factor GATA-2

1

11

High-throughput

0.479

High

697030

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

703104

TEAD1
Transcriptional enhancer factor TEF-1

1

4

High-throughput

0.479

High

754748

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.479

High

764503

CTNB1
Catenin beta-1

1

11

High-throughput

0.479

High

775805

HNF1B
Hepatocyte nuclear factor 1-beta

1

19

High-throughput

0.479

High

776032

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

776160

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

814759

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

814763

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

814765

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.479

High

814766

CENPA
Histone H3-like centromeric protein A

1

9

High-throughput

0.479

High

814768

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.479

High

814772

PAR2
Proteinase-activated receptor 2

1

10

High-throughput

0.479

High

814778

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

814779

RAB1A
Ras-related protein Rab-1A

1

11

High-throughput

0.479

High

814780

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.479

High

814784

H33
Histone H3.3

1

9

High-throughput

0.479

High

814785

TFAM
Transcription factor A, mitochondrial

1

20

High-throughput

0.479

High

814788

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

814789

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

1

High-throughput

0.479

High

814790

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

814795

SOX4
Transcription factor SOX-4

1

20

High-throughput

0.479

High

814797

RBBP4
Histone-binding protein RBBP4

1

9

High-throughput

0.479

High

814798

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

1

High-throughput

0.479

High

814800

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

14

High-throughput

0.479

High

814801

TP53B
TP53-binding protein 1

1

11

High-throughput

0.479

High

814802

FOXL1
Forkhead box protein L1

1

19

High-throughput

0.479

High

814804

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

814805

CBX3
Chromobox protein homolog 3

1

3

High-throughput

0.479

High

814806

SKP2
S-phase kinase-associated protein 2

1

8

Small-scale

0.479

High

814808

CUL1
Cullin-1

1

15

Small-scale

0.479

High

814816

FBW10
F-box/WD repeat-containing protein 10

1

18

High-throughput

0.479

High

814820

RICTR
Rapamycin-insensitive companion of mTOR

1

4

High-throughput

0.479

High

814822

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

814824

SMC5
Structural maintenance of chromosomes protein 5

1

18

High-throughput

0.479

High

814830

SP7
Transcription factor Sp7

1

11

High-throughput

0.479

High

814831

RBCC1
RB1-inducible coiled-coil protein 1

1

16

High-throughput

0.479

High

814832

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

814834

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

814839

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

14

High-throughput

0.479

High

814842

ZDH12
Palmitoyltransferase ZDHHC12

1

4

High-throughput

0.479

High

814846

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

814847

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

814848

FEV
Protein FEV

1

9

High-throughput

0.479

High

814855

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

10

High-throughput

0.479

High

814859

WWTR1
WW domain-containing transcription regulator protein 1

1

16

High-throughput

0.479

High

814861

RAB1B
Ras-related protein Rab-1B

1

10

High-throughput

0.479

High

814863

GAN
Gigaxonin

1

6

High-throughput

0.479

High

814868

ECT2
Protein ECT2

1

14

High-throughput

0.479

High

814871

ITM2C
Integral membrane protein 2C

1

4

High-throughput

0.479

High

814872

SAR1A
Small COPII coat GTPase SAR1A

1

20

High-throughput

0.479

High

814873

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.479

High

814876

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

814881

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

814883

ANC2
Anaphase-promoting complex subunit 2

1

16

High-throughput

0.479

High

814885

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

814886

NUP50
Nuclear pore complex protein Nup50

1

3

High-throughput

0.479

High

814892

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

814819

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

814890

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

296608

TNF13
Tumor necrosis factor ligand superfamily member 13

1

1

High-throughput

0.445

High

429441

JUN
Transcription factor Jun

1

11

High-throughput

0.445

High

765200

BMI1
Polycomb complex protein BMI-1

1

19

High-throughput

0.445

High

814771

NCBP2
Nuclear cap-binding protein subunit 2

1

9

High-throughput

0.445

High

814817

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.445

High

814826

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

4

High-throughput

0.445

High

814858

ZDHC5
Palmitoyltransferase ZDHHC5

1

7

High-throughput

0.445

High

814874

RN146
E3 ubiquitin-protein ligase RNF146

1

1

Small-scale

0.445

High

814878

GRHL1
Grainyhead-like protein 1 homolog

1

5

High-throughput

0.445

High

139822

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

182484

GP182
G-protein coupled receptor 182

1

9

High-throughput

0.437

High

293319

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

388117

ACHA
Acetylcholine receptor subunit alpha

1

2

High-throughput

0.437

High

411499

NTRK1
High affinity nerve growth factor receptor

1

17

High-throughput

0.437

High

575641

GPIX
Platelet glycoprotein IX

1

8

High-throughput

0.437

High

814782

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

2

High-throughput

0.437

High

814821

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

814825

S15A3
Solute carrier family 15 member 3

1

2

High-throughput

0.437

High

814841

PLPR2
Phospholipid phosphatase-related protein type 2

1

1

High-throughput

0.437

High

814845

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

1

High-throughput

0.437

High

814867

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

814869

LPAR2
Lysophosphatidic acid receptor 2

1

1

High-throughput

0.437

High

814884

KCND3
A-type voltage-gated potassium channel KCND3

1

4

Small-scale

0.437

High

814888

CLC4A
C-type lectin domain family 4 member A

1

5

High-throughput

0.437

High

814887

FZD10
Frizzled-10

1

0

High-throughput

0.426

High

220527

CAH12
Carbonic anhydrase 12

1

2

High-throughput

0.417

High

49154

POTB3
POTE ankyrin domain family member B3

1

5

High-throughput

0.407

High

104114

F5H1C8
Solute carrier family 15 member 3

1

2

High-throughput

0.407

High

814760

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

1

High-throughput

0.407

High

814767

CXCR3
C-X-C chemokine receptor type 3

1

8

High-throughput

0.407

High

303677

JTB
Protein JTB

1

0

High-throughput

0.279

Low

814815

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

814829

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

814856

TMM59
Transmembrane protein 59

1

0

High-throughput

0.279

Low

814862

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

814864

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

814889

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.279

Low

814891

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

1

0

High-throughput

0.279

Low

814853

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.249

Low

703994

5HT1E
5-hydroxytryptamine receptor 1E

1

0

High-throughput

0.232

Low

814809

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.232

Low

814828

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.232

Low

814833

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.232

Low

814840

BSCL2
Seipin

1

0

High-throughput

0.232

Low

814851

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025