Interactor 1: TOP1 (P04786)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) (Maintenance of killer protein 1)
Gene: TOP1
Interactor 2: SIZ1 (Q04195)
E3 SUMO-protein ligase SIZ1 (EC 2.3.2.-) (E3 SUMO-protein transferase SIZ2) (SAP and Miz-finger domain-containing protein 1) (Ubiquitin-like protein ligase 1)
Gene: SIZ1
Species: Saccharomyces cerevisiae S288C
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23712011 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0007059 - chromosome segregation |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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| + | Hs |  |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
